Pharmacokinetics of vorapaxar and its metabolite following oral administration in healthy Chinese and American subjects.

Xia Chen; Teddy Kosoglou; Paul Statkevich; Bharath Kumar; Jing Li; Marissa F Dockendorf; Guoqin Wang; Robert S Lowe; Ji Jiang; Hongzhong Liu; Zaiqi Wang; David L Cutler; Pei Hu

首页> 外文期刊>International journal of clinical pharmacology and therapeutics >Pharmacokinetics of vorapaxar and its metabolite following oral administration in healthy Chinese and American subjects.

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Pharmacokinetics of vorapaxar and its metabolite following oral administration in healthy Chinese and American subjects.

机译：沃拉普克萨尔的药代动力学及其在健康中美国科目中口服施用后的代谢产物。

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摘要

The pharmacokinetic profiles of vorapaxar and M20 and the metabolite/parent ratios in healthy Chinese were generally comparable to those in a healthy Western population.

机译：Vorapaxar和M20的药代动力学谱和健康中药中的代谢物/父母比例通常与健康西方人民群中的代谢物/亲本比率相媲美。

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来源
《International journal of clinical pharmacology and therapeutics》 |2014年第10期|共11页
作者
Xia Chen; Teddy Kosoglou; Paul Statkevich; Bharath Kumar; Jing Li; Marissa F Dockendorf; Guoqin Wang; Robert S Lowe; Ji Jiang; Hongzhong Liu; Zaiqi Wang; David L Cutler; Pei Hu;
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Department of Environment Security Territory Food and Health Sciences-Occupational Medicine;

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正文语种 eng
中图分类毒物学（毒理学）;
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1. Pharmacokinetics of vorapaxar and its metabolite following oral administration in healthy Chinese and American subjects. [J] . Xia Chen, Teddy Kosoglou, Paul Statkevich, International journal of clinical pharmacology and therapeutics . 2014,第10期

机译：在中国和美国的健康受试者中口服后，vorapaxar及其代谢产物的药代动力学。
2. EVALUATION OF PHARMACOKINETICS AND TOLERABILITY OF TAUROURSODEOXYCHOLIC ACID (T-UDCA) AND ITS METABOLITES AFTER A SINGLE ORAL ADMINISTRATION IN HEALTHY SUBJECTS. [J] . Park K., Lee S., Kim Y., Clinical Pharmacology and Therapeutics . 2016,第Suppla1期

机译：在健康受试者中单次口服后，牛磺二氧代乙酸（T-UDCA）及其代谢物的药代动力学和耐受性评估。
3. Pharmacokinetics and tolerability of duloxetine following oral administration to healthy Chinese subjects. [J] . Tianmei S, Knadler MP, Lim MT, Clinical pharmacokinetics . 2007,第9期

机译：口服度洛西汀对健康中国受试者的药代动力学和耐受性。
4. Serum and nail pharmacokinetic studies of itraconazole after mutiple oral dosing to 9 healthy chinese volunteers [C] . Chen Xiulan, Bai Lin, Lu xiaochuna, Proceedings of the Fourth China-Jpan international congress of mycology . 1998

机译：对9名健康中国志愿者进行多次口服给药后伊曲康唑的血清和指甲药代动力学研究
5. C-Reactive Protein as a Biomarker of Oral Health and Risk of Cardiovascular Disease in Healthy and CV Disease Subjects. [D] . Alzalzalah, Ahmed. 2017

机译：C反应蛋白是健康和CV疾病受试者口腔健康和心血管疾病风险的生物标志物。
6. The pharmacokinetics tolerability and pharmacodynamics of tucaresol (589C80; 42-formyl-3-hydroxyphenoxymethyl benzoic acid) a potential anti-sickling agent following oral administration to healthy subjects. [O] . P E Rolan, J E Parker, S J Gray, 1993

机译：在向健康受试者口服后Tucaresol（589C80; 4 2-甲酰基-3-羟基苯氧基甲基苯甲酸）的药代动力学耐受性和药效学是一种潜在的抗溶血剂。
7. The pharmacokinetics, tolerability and pharmacodynamics of tucaresol (589C80; 4[2-formyl-3-hydroxyphenoxymethyl] benzoic acid), a potential anti-sickling agent, following oral administration to healthy subjects. [O] . Rolan, P E, Parker, J E, Gray, S J, 1993

机译：在向健康受试者口服后，Tucaresol（589C80; 4 [2-甲酰基-3-羟基苯氧基甲基]苯甲酸）的药代动力学，耐受性和药效学是一种潜在的抗溶血剂。

Pharmacokinetics of vorapaxar and its metabolite following oral administration in healthy Chinese and American subjects.

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