首页> 外文期刊>Advanced Powder Technology: The internation Journal of the Society of Powder Technology, Japan >Ultrasonically assisted fabrication of vaterite submicron-sized carriers
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Ultrasonically assisted fabrication of vaterite submicron-sized carriers

机译:超声辅助制备球ate石亚微米级载体

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Ultrasonically accomplished precipitation of calcium carbonate was demonstrated as a novel beneficial method for the formation of porous submicron vaterite particles with low dispersity, high mass yield, and the "scaling up" possibility. The effect of sonication on the size and crystallographic phase of formed particles was investigated by comparing this method with a magnetic stirring and non-stirring interfusion. By virtue of their porosity, vaterite particles allow the different substance incorporation. The loading properties of synthesized particles were demonstrated for high molecular weight substance (labeled protein), as well as for low molecular one (fluorescent dye). Such features open up perspectives of drug encapsulation and delivery for the vaterite submicron carriers. (C) 2016 The Society of Powder Technology Japan. Published by Elsevier B.V. and The Society of Powder Technology Japan. All rights reserved.
机译:超声完成碳酸钙的沉淀被证明是一种新颖的有益方法,用于形成具有低分散性,高产率和“放大”可能性的多孔亚微米球ate石颗粒。通过将这种方法与磁力搅拌和非搅拌式灌注相比较,研究了超声处理对所形成颗粒的尺寸和结晶相的影响。球ate石颗粒由于其多孔性,可以掺入不同的物质。证明了合成颗粒对高分子量物质(标记蛋白质)和低分子物质(荧光染料)的负载特性。这些特征为球ate石亚微米载体的药物封装和递送开辟了前景。 (C)2016日本粉末技术学会。由Elsevier B.V.和日本粉末技术学会出版。版权所有。

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