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Long-term radiographic appearance of calcium-phosphate synthetic bone grafts after surgical treatment of tibial plateau fractures

机译:钙磷酸盐合成骨移植的长期放射照相外观胫骨平台骨折外科治疗后

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Abstract Objectives Synthetic bone grafts (SBGs) are widely used to fill bone defects after fracture reduction. This study assessed the long-term resorption of two different calcium phosphate products (A=ChronOS? inject and B=Norian ? SRS ? ; both DePuy Synthes, Oberdorf, Switzerland) used in the surgical treatment of tibial plateau fractures. Design Long-term clinical and radiologic follow-up of 52 patients after surgical treatment of intraarticular tibial plateau fractures augmented with SBGs. Setting The study was performed at a level 3 trauma center. Patients Between January 2000 and December 2006 a total of 52 patients with intraarticular tibial plateau fractures were operatively treated and augmented with SBGs consisting of a Brushite matix with β-TCP granules (SBG A) or hydroxylapatite with 4–6% carbonate content (SBG B). 46 patients could be contacted and 38 were included in the study. Half of the patients received SBG A and the other half SBG B. Main outcome measurements Loss of reduction and SBG resorption was investigated by comparison of follow-up X-ray images to pre- and postoperative X-ray images. Furthermore, pain, activity level and knee function were evaluated by means of questionnaires and clinical examination. Results The mean age of patients was 59.7±12.5years. The follow-up was 8.6±0.9years for SBG A and 11.6±1.4years for SBG B (p 2mm) could be observed in two patients with SBG A and two patients with SBG B, although only one of them had an impaired knee function. Conclusions The composite SBG A reveals a comprehensive long-term resorption in comparison to SBG B. Nevertheless, both provided suitable mechanical support as part of the surgical treatment of tibial plateau fractures. Level of evidence Case series, Level IV.
机译:摘要目的,合成骨移植(SBG)被广泛用于在断裂后填充骨缺损。该研究评估了两种不同磷酸钙产品的长期吸收(A = Chronos?注入和B =诺里安?SRS?; Depuy Synthes,Oberdorf,瑞士)用于胫骨平台骨折的手术治疗。设计长期临床和放射学随访52名患者的外科治疗后的胫骨内胫骨平台骨折,增强了SBG。设置该研究在3级创伤中心进行。 2000年1月至2006年12月之间的患者共有52例患有细胞内胫骨平台骨折的患者,并用SBG组成,与β-TCP颗粒(SBG A)或羟基磷灰石组成的SBG组成,具有4-6%碳酸盐含量(SBG B. )。可以联系46名患者,研究中包含38例。一半的患者接受了SBG A和另一半SBG B.通过将随访X射线图像进行比较和术后X射线图像进行了研究,研究了损失和SBG吸收的主要结果测量。此外,通过问卷调查和临床检查评估疼痛,​​活性水平和膝关节功能。结果患者的平均年龄为59.7±12.5岁。后续随访时间为8.6±0.9年,SBG A和SBG B的11.6±1.4°,可以在两名SBG A和SBG B患者中观察到SBG B(P 2mm),尽管他们中只有一个膝关节功能。结论综合SBG A与SBG B相比,概念揭示了综合性长期吸收,无论如何,两者都提供了合适的机械支撑,作为胫骨平台骨折的手术治疗的一部分。证据案例系列,IV级。

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