Copper(II) and cadmium(II) complexes derived from Strandberg-type polyoxometalate clusters: Synthesis, crystal structures, spectroscopy and biological activities

摘要

Three Strandberg-type polyoxometalate compounds [Cu(L)(2)(H2O)(2)](2)H-2[P2Mo5O23]center dot 2CH(3)OH (1), [Cu(L)(2)(H2O)]H-2[Cu(L)(2)(P2Mo5O23)]center dot 4H(2)O (2), [Cd(L)(2)(H2O)(2)](2)H-2[P2Mo5O23]center dot 2CH(3)OH (3), (L = pyridine-2carboxamide) have been synthesized and structurally characterized by elemental analysis, spectroscopic methods (IR and UV-vis) as well as single crystal X-ray diffraction. Single-crystal X-ray structural analyses indicate that 1 and 3 are isostructural and crystallized in monoclinic, space group 12/a. Biological studies have indicated that compounds 1-3 exhibit broad and effective activities against the tested cells. A synergistic effect involving L, metal and P2Mo5 could probably explain the improved growth-inhibiting properties. Both coordination mode and the type of metal ion play significant roles in these compounds cytotoxicity. (C) 2017 Elsevier B.V. All rights reserved.