Synthesis and catalytic application of D-glucose derived ytterbium(III) complex in Biginelli reaction

摘要

4,6-O-Ethylidene N-(2-hydroxybenzylidene)-beta-D-glucopyranosylamine has been reacted with ytterbium(III) acetate and the resultant complex has been used as catalyst in the synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones (DHPMs). Twenty-one DHPMs have been synthesised under neat reaction condition in appreciable yields (73-96%) and reusability of the catalyst has been established.