Influence of mechanical thrombectomy on the prognosis of stroke induced by intracranial large vessel occlusion

摘要

Objective: To investigate the influence of mechanical thrombectomy on the prognosis of stroke caused by intracranial large vessel occlusion. Methods: A single-center, prospective, randomized, double-blind controlled trial was conducted in 98 patients with acute ischemic stroke. These patients were randomly divided into the control group and the experimental group. For the control group, patients received intravenous thrombolytic therapy. According to the causes of vascular occlusion, patients in the experimental group were treated with appropriate mechanical thrombectomy. Therapeutic effects, hospitalization time, treatment costs, vessel recanalization rates, and complications were compared between the two groups. Results: The therapeutic effect, vessel recanalization rate, and treatment cost in the experimental group were significantly higher than those in the control group (all P<0.05). However, hospitalization time and National Institute of Health stroke scale (NIHSS) score in the experimental group were significantly decreased compared with the control group (all P<0.05). What's more, there was no significant difference concerning complications between the two groups (P>0.05). Conclusion: Compared with intravascular thrombolytic therapy, the treatment based on the causes of vascular occlusion is accurate, and does not increase the incidence of complications, which is worth promoting in clinical practice.