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A composite nonparametric product limit approach for estimating the distribution of survival times under length-biased and right-censored data

机译:一种复合非参数产品限制方法,用于估计长度偏见和右缩义数据下的存活时间分布

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This paper considers a composite nonparametric product limit estimator for estimating the distribution of survival times when the data are length-biased and right censored. Our method takes into account auxiliary information that frequently arises in survival analysis, and is easier to implement than existing methods for estimating survival functions. We derive a strong representation of the proposed estimator, establish its consistency and asymptotic normality, and derive its convergence rate of approximation. As well, we prove that auxiliary information improves the asymptotic efficiency of the proposed estimator, and provide the values of the composite weights that result in the largest efficiency gain. Our proposed estimator fares well in comparison with other more complex methods in finite samples and offers a clear advantage with respect to computational time.
机译:本文考虑了复合非参数产品限制估计器,用于估算数据偏差和右审查的数据时存活时间的分布。 我们的方法考虑了经常出现在生存分析中的辅助信息,并且比现有方法更容易实现用于估算生存功能的方法。 我们派生建议估计的强烈代表性,建立了其一致性和渐近常态,并导出其近似的收敛速度。 同样,我们证明辅助信息提高了所提出的估计器的渐近效率,并提供了导致最大效率增益的复合权重的值。 我们提出的估算们与有限样本中的其他更复杂的方法相比,我们在有限样本中的其他更复杂的方法比较,并对计算时间提供了明显的优势。

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