The correlation between procalcitonin and D-dimer and the prognoses of emergency sepsis patients

摘要

Objective: To study the correlation between procalcitonin (PCT) and D-dimer (DD) levels and their impact on the prognoses of emergency sepsis patients. Methods: We included 92 sepsis patients and 50 non-sepsis patients who were diagnosed during the same period. The sepsis patients were divided into a sepsis group and a septic shock group according to disease severity and additionally divided into a survival group and death group according to 28-day survival. The levels of PCT and DD were measured after 7 days of treatment, and the severity and prognoses of the patients were compared. Results: The levels of PCT and DD were significantly higher in the sepsis patients than in the non-sepsis patients (both P<0.05). The PCT and DD levels were significantly lower in the sepsis group than in the septic shock group (both P<0.05). The PCT and DD levels were significantly lower in the survival group than in the death group (both P<0.05). The ROC curve of PCT combined with DD was statistically different from that of PCT and DD alone (P=0.048 and P=0.017). Conclusions: The clinical application of PCT combined with DD is valuable in predicting the severity and prognosis of sepsis and is worthy of further study.