Multicentre investigation of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in Bulgarian hospitals - Interregional spread of ST11 NDM-1-producing K. pneumoniae

Markovska Rumyana; Stoeva Temenuga; Boyanova Lyudmila; Stankova Petya; Schneider Ines; Keuleyan Emma; Mihova Kalina; Murdjeva Marianna; Sredkova Mariya; Lesseva Magdalena; Nedelcheva Gergana; Petrova Atanaska; Ivanova Dobrinka; Lazarova Grozdanka; Kaneva Radka; Mitov Ivan

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Multicentre investigation of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in Bulgarian hospitals - Interregional spread of ST11 NDM-1-producing K. pneumoniae

机译：保加利亚医院碳碱酶促蛋白酶肺炎肺炎和大肠杆菌的多元调查 - ST11 NDM-1生产K.肺炎的区域间传播

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Aim: The aim of this study was to investigate the mechanisms of beta-lactam-resistance and the clonal relatedness of carbapenem-nonsusceptible Klebsiella pneumoniae and Escherichia coli isolates, collected consecutively in eight centers in five Bulgarian cities from November 2014 to March 2018. Carbapenemase-producing enterobacteria were detected in all but one centers. Overall, 104 K. pneumoniae and one E. coli were analysed.

机译：目的：本研究的目的是探讨β-内酰胺抗性和克林涅姆 - 非肌肉皮骨菌和大肠杆菌的克隆相关性的机制，从2014年11月到2018年11月的五个保加利亚城市的八个中心在八个中心收集。 - 除了一个中心之外，还检测到癌症肠癌。总体而言，分析了104k.Pneumoniae和一个大肠杆菌。

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来源
《Infection, Genetics and Evolution: Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases》 |2019年第2019期|共7页
作者
Markovska Rumyana; Stoeva Temenuga; Boyanova Lyudmila; Stankova Petya; Schneider Ines; Keuleyan Emma; Mihova Kalina; Murdjeva Marianna; Sredkova Mariya; Lesseva Magdalena; Nedelcheva Gergana; Petrova Atanaska; Ivanova Dobrinka; Lazarova Grozdanka; Kaneva Radka; Mitov Ivan;
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作者单位

Med Univ Sofia Dept Med Microbiol Med Fac 1 Georgi Sofiiski 1431 Sofia Bulgaria;

Med Univ Varna Dept Microbiol &

Virol UMHAT St Marina Varna Bulgaria;

Med Univ Sofia Dept Med Microbiol Med Fac 1 Georgi Sofiiski 1431 Sofia Bulgaria;

Med Univ Sofia Dept Med Microbiol Med Fac 1 Georgi Sofiiski 1431 Sofia Bulgaria;

MICOER Inst Munich Germany;

Minist Interior Med Inst Dept Clin Microbiol Sofia Bulgaria;

Med Univ Sofia Mol Med Ctr Sofia Bulgaria;

Med Univ Plovdiv Dept Microbiol &

Immunol UMHAT Plovdiv Bulgaria;

Med Univ Pleven Dept Microbiol &

Virol UMHAT Georgi Stranski Pleven Bulgaria;

Emergency Med Inst Pirogov Sofia Bulgaria;

Med Univ Varna Dept Microbiol &

Virol UMHAT St Marina Varna Bulgaria;

Second Multiprofile Hosp Active Treatment Sofia Bulgaria;

Thracian Univ UMHAT Prof Dr St Kirkovich Stara Zagora Stara Zagora Bulgaria;

Med Univ Sofia Mol Med Ctr Sofia Bulgaria;

Med Univ Sofia Dept Med Microbiol Med Fac 1 Georgi Sofiiski 1431 Sofia Bulgaria;

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原文格式 PDF
正文语种 eng
中图分类预防医学、卫生学;
关键词
Bulgaria; Carbapenemases; NDM; KPC; K. pneumoniae; E. coli;

机译：保加利亚;疾病;ndm;kpc;k。肺炎;e。植物植物;

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专利

1. Multicentre investigation of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in Bulgarian hospitals - Interregional spread of ST11 NDM-1-producing K. pneumoniae [J] . Markovska Rumyana, Stoeva Temenuga, Boyanova Lyudmila, Infection, Genetics and Evolution: Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases . 2019,第期

机译：保加利亚医院碳碱酶促蛋白酶肺炎肺炎和大肠杆菌的多元调查 - ST11 NDM-1生产K.肺炎的区域间传播
2. Use of WGS data for investigation of a long-term NDM-1-producing Citrobacter freundii outbreak and secondary in vivo spread of bla(NDM-1) to Escherichia coli, Klebsiella pneumoniae and Klebsiella oxytoca [J] . Hammerum Anette M., Hansen Frank, Nielsen Hans Linde, The Journal of Antimicrobial Chemotherapy . 2016,第11期

机译：使用WGS数据调查长期产生NDM-1的弗氏柠檬酸杆菌暴发以及bla（NDM-1）在体内向大肠杆菌，肺炎克雷伯菌和产氧克雷伯菌的继发性体内传播
3. Spreading of extended-spectrum β-lactamase-producing Escherichia coli ST131 and Klebsiella pneumoniae ST11 in patients with pneumonia: a molecular epidemiological study [J] . Jing Liu, Shuai-Xian Du, Jin-Nong Zhang, 中华医学杂志（英文版） . 2019,第016期

机译：产生大范围β-内酰胺酶的大肠杆菌ST131和肺炎克雷伯菌ST11在肺炎患者中的传播：分子流行病学研究
4. Optimization of expression conditions of dhaT gene from Klebsiella pneumoniae in Escherichia coli using uniform design [C] . China-Japan-Korea Joint Symposium on Enzyme Engineering . 2004

机译：均匀设计法优化肺炎克雷伯菌dhaT基因在大肠杆菌中的表达条件。
5. Lipopolysaccharide inner core oligosaccharide biosynthesis and outer membrane stability in Escherichia coli and Klebsiella pneumoniae. [D] . Frirdich, Emilisa. 2005

机译：脂多糖内核寡糖的生物合成和外膜在大肠杆菌和肺炎克雷伯菌中的稳定性。
6. Spreading of extended-spectrum β-lactamase-producing Escherichia coli ST131 and Klebsiella pneumoniae ST11 in patients with pneumonia: a molecular epidemiological study [O] . Jing Liu, Shuai-Xian Du, Jin-Nong Zhang, 2019

机译：产生大范围β-内酰胺酶的大肠杆菌ST131和肺炎克雷伯氏菌ST11在肺炎患者中的传播：分子流行病学研究
7. Three bacterium-plasmid golden combinations facilitate the spread of ST11/CG258 carbapenemase-producing Klebsiella pneumoniae in China [O] . Cuidan Li, Xiaoyuan Jiang, Tingting Yang, 2021

机译：三种细胞质粒金色组合有助于在中国的ST11 / CG258碳结构酶的肺炎蛋白酶肺炎

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Multicentre investigation of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in Bulgarian hospitals - Interregional spread of ST11 NDM-1-producing K. pneumoniae

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