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首页> 外文期刊>Infection, Genetics and Evolution: Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases >An HLA class II locus, previously identified by a genome-wide association study, is also associated with susceptibility to pulmonary tuberculosis in a Chinese population
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An HLA class II locus, previously identified by a genome-wide association study, is also associated with susceptibility to pulmonary tuberculosis in a Chinese population

机译:以前由基因组关联研究鉴定的HLA类基因座也与中国人口中肺结核的易感性有关

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摘要

Objective: Genome-wide association study (GWAS) in Icelanders identified HLA class II sequence variants on chromosome 6p21 as tuberculosis (TB) susceptibility loci. To evaluate the role of these loci in other populations with different ancestry, we conducted a case-control study in Chinese population.
机译:目的:冰冰的基因组协会研究(GWAS)在染色体6P21上鉴定了HLA类II序列变体作为结核病(TB)易感性基因座。 为了评估这些基因座在其他血统中的其他人群中的作用,我们对中国人口进行了案例对照研究。

著录项

  • 来源
  • 作者单位

    Nanjing Municipal Ctr Dis Control &

    Prevent Dept Chron Communicable Dis 2 Zi Zhu Lin Nanjing 210003 Jiangsu Peoples R China;

    Nanjing Hosp Chinese Med 1 Jinling Rd Nanjing 210001 Jiangsu Peoples R China;

    Nanjing Municipal Ctr Dis Control &

    Prevent Dept Chron Communicable Dis 2 Zi Zhu Lin Nanjing 210003 Jiangsu Peoples R China;

    Nanjing Municipal Ctr Dis Control &

    Prevent Dept Chron Communicable Dis 2 Zi Zhu Lin Nanjing 210003 Jiangsu Peoples R China;

    Nanjing Municipal Ctr Dis Control &

    Prevent Dept Chron Communicable Dis 2 Zi Zhu Lin Nanjing 210003 Jiangsu Peoples R China;

    Nanjing Municipal Ctr Dis Control &

    Prevent Dept Chron Communicable Dis 2 Zi Zhu Lin Nanjing 210003 Jiangsu Peoples R China;

    Nanjing Municipal Ctr Dis Control &

    Prevent Dept Chron Communicable Dis 2 Zi Zhu Lin Nanjing 210003 Jiangsu Peoples R China;

    Nanjing Municipal Ctr Dis Control &

    Prevent Dept Chron Communicable Dis 2 Zi Zhu Lin Nanjing 210003 Jiangsu Peoples R China;

    Nanjing Hosp Chinese Med 1 Jinling Rd Nanjing 210001 Jiangsu Peoples R China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 预防医学、卫生学;
  • 关键词

    Tuberculosis; Susceptibility; HLA; Polymorphism;

    机译:结核病;易感性;HLA;多态性;

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