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Susceptibility of Candida auris and Candida albicans to 21 germicides used in healthcare facilities

机译:Candida Auris和Candida albicans对医疗保健设施中使用的21种杀菌剂的易感性

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摘要

Candida auris is an emerging fungal pathogen that is often resistant to major classes of antifungal drugs. It is considered a serious global health threat because it can cause severe infections with frequent mortality in more than a dozen countries. It can survive on healthcare environmental surfaces for at least 7 days and can cause outbreaks in healthcare facilities. Clearly, infection prevention strategies, such as surface disinfection, will be essential to controlling Candida transmission. Unfortunately, data on the activity of antiseptics and disinfectants used in healthcare to inactivate this pathogen are limited.1–5 In this study, we investigated 12 different disinfectants (ie, 8 low- and intermediate-level disinfectants in 2 dilutions of sodium hypochlorite and 5 high-level disinfectants/chemical sterilants) and 9 antiseptics commonly used in healthcare facilities for their antimicrobial activity against C. auris and C. albicans.
机译:Candida Auris是一种新兴的真菌病原体,通常是抗真菌药物的主要类别。 它被认为是严重的全球健康威胁,因为它可能导致超过十几个国家的频繁死亡率的严重感染。 它可以在医疗保健环境表面上存活至少7天,并可能导致医疗保健设施的爆发。 显然,诸如表面消毒等感染策略对控制念珠菌传输至关重要。 遗憾的是,关于医疗保健用于灭活该病原体的抗菌剂和消毒剂的数据是有限的.1-5在这项研究中,我们研究了12种不同的消毒剂(即,2次稀释次稀释剂中的8个低和中间水平消毒剂和次氯酸钠 5个高水平消毒剂/化学灭菌剂)和9个抗菌剂,常用于医疗保健设施,用于对C. auris和C. albicans进行抗微生物活性。

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