Clinical Profile and Hepatitis B And C Viral Markers in Acute and Chronic Liver Disease in DMCH, Laheriasarai, Bihar

摘要

BACKGROUND AND OBJECTIVE: Hepatitis B and Hepatitis C virus are endemic in India and have an aetiological role in acute hepatitis, 50-70% of which end up with chronic liver disease. Hepatitis B is responsible for approximately 300 million cases of chronic liver disease worldwide and is the leading cause of chronic hepatitis, cirrhosis and hepatocellular carcinoma worldwide. Hepatitis C is the major cause of transfusion transmitted non-A and non-B hepatitis and continues to be a major cause of liver disease throughout the world. As there are limited number of studies regarding this, the present study is undertaken. METHODOLOGY : One hundred patients with liver disease attending outpatient department and admitted as inpatients at Darbhanga Medical College & Hospital, Laheriasarai, Bihar were taken for the study. RESULTS : One hundred patients with liver disease were studied. Majority of patients were in mean age group of 41-60 years. Male to female ratio was 4:1. Majority of patients presented with abdominal distension, anorexia and jaundice. All the 100 patients had abnormal liver function test. 30% patients had viral markers in the form of HBsAg in 26% and anti HCV in 4% cases. CONCLUSION : Hepatitis B and C are the major causes of chronic liver disease.