A Case-control Study Screening the Correlation of Chromosomal Alterations with Male Infertility in 180 Infertile Men from North Maharashtra

摘要

Purpose: To examine the association between chromosomal abnormalities and male infertility. Objectives: To find out the frequency and types of chromosomal alterations; major chromosomal abnormalities and polymorphic chromosomal variants in infertile males and to assess its impact on male infertility. Design: It is a case-control study, carried out on peripheral blood lymphocytes with standard G-banding technique in infertile males versus control fertile males. It is a type of observational study and comes under the analytical study because in this type of study comparison (control) group is used. Patient(s): 180 infertile men and 60 control fertile men.