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DEVELOPMENT AND IN VIVO STUDIES OF HERBAL HAIR OIL FOR HAIR GROWTH PROMOTION

机译:发育中草发油的发展与体内研究

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Alopecia or baldness is a very common dermatological disorder. In the present study a herbal hair oil for hair growth promotion was formulated and evaluated for its hair growth potential. The olive oil based herbal hair oil was prepared from the seeds of Trigonella foenum-graecum treated with Aloe vera gel (prepared with fresh Aloe vera leaves). The prepared oil was subjected to characterization for various physicochemical parameters like acid value, iodine value, saponification value, peroxide value, refractive index, specific gravity, odour and taste. All these values conformed to compendia requirements. Hair growth activity of the developed oil was studied in comparison of 2 % minoxidil solution (standard) in albino rats for 30 days. The hair growth initiation time of prepared herbal oil (5 days) was even less than that of standard or minoxidil-treated groups (8 days). The herbal oil also showed the least hair growth completion time (18 days) in comparison of standard (21 days) and control (25 days). With the treatment of herbal oil, the hair length as well as diameter was also considerably increased as compared to control and standard. It was concluded that the prepared olive oil based herbal hair oil of Trigonella has potential components to stimulate hair growth even in short term treatment.
机译:脱发或秃头是一种非常常见的皮肤病。在本研究中,制备了用于毛发生生长促进的草原发油,并评估其毛发生长潜力。橄榄油的草原发油是由用芦荟凝胶处理的三角形Foenum-Graecum的种子制备(用新鲜的芦荟叶制备)。对制备的油进行酸值,碘值,皂化值,过氧化物值,折射率,比重,气味和味道等各种物理化学参数表征。所有这些值都符合Compendia要求。研究了发育油的毛发生生长活性在白化大鼠中的2%Minoxidil溶液(标准)进行了30天。制备草药(5天)的毛发生生长起始时间甚至小于标准或明氧比处理的基团(8天)。与标准(21天)和对照(25天)相比,草本油还显示出毛发生生长完成时间(18天)。通过治疗草本油,与对照和标准相比,头发长度以及直径也大大增加。得出结论是,即使在短期治疗中,制备的三角形的橄榄油的草原发油也具有潜在的成分,以刺激毛发生长。

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