DESIGN, SYNTHESIS AND EVALUATION OF NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS ANTICANCER AGENTS

摘要

A new series of substituted benzimidazoie derivatives was synthesis and the structures of these compounds were established on the basis of spectral data. The title compounds were evaluated for in vitro anticancer activity against MCF - 7 and NCI-H226 cell line. Some of these compounds have shown high anticancer activity.