NPM1 mutant variant allele frequency correlates with leukemia burden but does not provide prognostic information in NPM1-mutated acute myeloid leukemia

Abbas Hussein A.; Ravandi Farhad; Loghavi Sanam; Patel Keyur P.; Borthakur Gautam; Kadia Tapan M.; Jabbour Elias; Takahashi Koichi; Cortes Jorge; Issa Ghayas C.; Konopleva Marina; Kantarjian Hagop M.; Short Nicholas J.

首页> 外文期刊>American Journal of Hematology >NPM1 mutant variant allele frequency correlates with leukemia burden but does not provide prognostic information in NPM1-mutated acute myeloid leukemia

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NPM1 mutant variant allele frequency correlates with leukemia burden but does not provide prognostic information in NPM1-mutated acute myeloid leukemia

机译：NPM1突变体变异等位基因频率与白血病负担相关，但不提供NPM1突变的急性髓性白血病的预后信息

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来源
《American Journal of Hematology》 |2019年第6期|共3页
作者
Abbas Hussein A.; Ravandi Farhad; Loghavi Sanam; Patel Keyur P.; Borthakur Gautam; Kadia Tapan M.; Jabbour Elias; Takahashi Koichi; Cortes Jorge; Issa Ghayas C.; Konopleva Marina; Kantarjian Hagop M.; Short Nicholas J.;
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作者单位

Univ Texas MD Anderson Canc Ctr Hematol &

Oncol Fellowship Program Houston TX 77030 USA;

Univ Texas MD Anderson Canc Ctr Dept Leukemia 1515 Holcombe Blvd Unit 428 Houston TX 77030 USA;

Univ Texas MD Anderson Canc Ctr Dept Hematopathol Houston TX 77030 USA;

Univ Texas MD Anderson Canc Ctr Dept Hematopathol Houston TX 77030 USA;

Univ Texas MD Anderson Canc Ctr Dept Leukemia 1515 Holcombe Blvd Unit 428 Houston TX 77030 USA;

Univ Texas MD Anderson Canc Ctr Dept Leukemia 1515 Holcombe Blvd Unit 428 Houston TX 77030 USA;

Univ Texas MD Anderson Canc Ctr Dept Leukemia 1515 Holcombe Blvd Unit 428 Houston TX 77030 USA;

Univ Texas MD Anderson Canc Ctr Dept Leukemia 1515 Holcombe Blvd Unit 428 Houston TX 77030 USA;

Univ Texas MD Anderson Canc Ctr Dept Leukemia 1515 Holcombe Blvd Unit 428 Houston TX 77030 USA;

Univ Texas MD Anderson Canc Ctr Dept Leukemia 1515 Holcombe Blvd Unit 428 Houston TX 77030 USA;

Univ Texas MD Anderson Canc Ctr Dept Leukemia 1515 Holcombe Blvd Unit 428 Houston TX 77030 USA;

Univ Texas MD Anderson Canc Ctr Dept Leukemia 1515 Holcombe Blvd Unit 428 Houston TX 77030 USA;

Univ Texas MD Anderson Canc Ctr Dept Leukemia 1515 Holcombe Blvd Unit 428 Houston TX 77030 USA;

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正文语种 eng
中图分类血液及淋巴系疾病;
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1. NPM1 mutant variant allele frequency correlates with leukemia burden but does not provide prognostic information in NPM1-mutated acute myeloid leukemia [J] . Abbas Hussein A., Ravandi Farhad, Loghavi Sanam, American Journal of Hematology . 2019,第6期

机译：NPM1突变体变异等位基因频率与白血病负担相关，但不提供NPM1突变的急性髓性白血病的预后信息
2. Impact of the variant allele frequency of ASXL1 ASXL1 , DNMT3A DNMT3A , JAK2 JAK2 , TET2 TET2 , TP53 TP53 , and NPM1 NPM1 on the outcomes of patients with newly diagnosed acute myeloid leukemia [J] . Sasaki Koji, Kanagal‐Shamanna Rashmi, Montalban‐Bravo Guillermo, Cancer: A Journal of the American Cancer Society . 2020,第4期

机译：ASX11AS11，DNMT3A DNMT3A，JAK2 JAK2，TET2 TET2，TP53 TP53和NPM1 NPM1对新诊断的急性髓性白血病患者结果的影响
3. Prognostic Significance of Baseline FLT3-ITD Mutant Allele Burden in Acute Myeloid Leukemia Treated with Intensive Chemotherapy with/without Sorafenib [J] . Yalniz Fevzi, Kantarjian Hagop M., Kadia Tapan M., Blood: The Journal of the American Society of Hematology . 2018,第NovaelaTreatmentAppr期

机译：基线FLT3-ITD突变体等急性髓性白血病患者急性化疗治疗的预后意义，用索拉染料治疗
4. K-Means Clustering on 3^rd order polynomial based normalization of Acute Myeloid Leukemia (AML) and Acute Lymphocyte Leukemia (ALL) [C] . Mehdi A.M., Sehgal M.S., Zayegh A., Electrical Engineering, 2009. ICEE '09 . 2009

机译：基于3 ^{rd 多项式的K均值聚类基于急性髓细胞白血病（AML）和急性淋巴细胞白血病（ALL）的归一化}
5. Prognostic analysis according to the 2017 ELN risk stratification by genetics in adult acute myeloid leukemia patients treated in the Japan Adult Leukemia Study Group (JALSG) AML201 study [D] . Harada Yasuhiko, 原田靖彦 2019

机译：根据2017年日本成人白血病研究组（JALSG）AML201研究治疗的成人急性髓性白血病患者的遗传学预测，根据2017 ELN风险分层进行预后分析
6. Analysis of NPM1 splice variants reveals differential expression patterns of prognostic value in acute myeloid leukemia [O] . Malgorzata Zajac, Anna Dolnik, Grazyna Stasiak, 2017

机译：NPM1剪接变体的分析揭示了急性髓样白血病预后价值的差异表达模式
7. Clinical relevance of IDH1/2 mutant allele burden during follow-up in acute myeloid leukemia. A study by the French ALFA group [O] . Yann Ferret, Nicolas Boissel, Nathalie Helevaut, 2018

机译：IDH1 / 2突变等位基因负担在急性髓性白血病随访期间的临床相关性。法国阿尔法集团的一项研究

NPM1 mutant variant allele frequency correlates with leukemia burden but does not provide prognostic information in NPM1-mutated acute myeloid leukemia

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