Attention-deficit/hyperactivity disorder and co-varying aggression - a relationship with serotonin-dependent impulsive and physiological trait moderators?

摘要

The relationship between attention-deficit/hyper-activity disorder (ADHD) and aggressive behaviour has been the subject of considerable research involving animals and humans (1-9). Evidence suggests that neurobiological and environmental factors contribute to different phenotypes of aggression as represented within the diagnosis of ADHD, conduct disorder (CD) and antisocial personality disorder (ASP) (10), and with opposi-tional defiant disorder (ODD) also being a part of the ADHD-aggression spectrum.