Review: Statins reduce mortality and cardiovascular events in adults at risk for cardiovascular disease

摘要

Included studies compared statins with control treatment (placebo, active control, or usual care) in adults without established CVD but with CVD risk factors. Primary outcome was all-cause mortality;secondary outcomes included major coronary events (death from coronary heart disease or nonfatal myocardial infarction), major cerebrovascular events (fatal or nonfatal stroke), and cancer.