BMP4 mutations in tooth agenesis and low bone mass

Yu Miao; Wang Hao; Fan Zhuangzhuang; Xie Chencheng; Liu Haochen; Liu Yang; Han Dong; Wong Sing-Wai; Feng Hailan

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BMP4 mutations in tooth agenesis and low bone mass

机译：BMP4牙齿血肿和低骨质量突变

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摘要

Objective: To identify an uncommon genetic cause of tooth agenesis (TA) by utilizing whole exome sequencing (WES) and targeted Sanger sequencing in a cohort of 120 patients with isolated TA.

机译：目的：利用整个exome测序（WES）和靶向Sanger测序在120例分离的TA型患者的群组中鉴定牙齿发育（TA）的罕见遗传原因。

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来源
《Archives of Oral Biology 》 |2019年第2019期| 共7页
作者
Yu Miao; Wang Hao; Fan Zhuangzhuang; Xie Chencheng; Liu Haochen; Liu Yang; Han Dong; Wong Sing-Wai; Feng Hailan;
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作者单位

Peking Univ Sch &

Hosp Stomatol Beijing Key Lab Digital Stomatol Dept Prosthodont Natl Clin Res;

Peking Univ Sch &

Hosp Stomatol Beijing Key Lab Digital Stomatol Dept Prosthodont Natl Clin Res;

Peking Univ Sch &

Hosp Stomatol Beijing Key Lab Digital Stomatol Dept Prosthodont Natl Clin Res;

Univ South Dakota Sanford Med Sch Dept Internal Med Sioux Falls SD 57105 USA;

Peking Univ Sch &

Hosp Stomatol Beijing Key Lab Digital Stomatol Dept Prosthodont Natl Clin Res;

Peking Univ Sch &

Hosp Stomatol Beijing Key Lab Digital Stomatol Dept Prosthodont Natl Clin Res;

Peking Univ Sch &

Hosp Stomatol Beijing Key Lab Digital Stomatol Dept Prosthodont Natl Clin Res;

Univ North Carolina Chapel Hill Adams Sch Dent Dept Periodontol Brauer Hall 7450 Chapel Hill;

Peking Univ Sch &

Hosp Stomatol Beijing Key Lab Digital Stomatol Dept Prosthodont Natl Clin Res;

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原文格式 PDF
正文语种 eng
中图分类口腔科学 ;
关键词
BMP4; Dental anomalies; Tooth agenesis; Osteopenia; Osteoporosis;

机译：BMP4;牙齿异常;牙齿血肿;骨质症;骨质疏松症;

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专利

1. BMP4 mutations in tooth agenesis and low bone mass [J] . Yu Miao, Wang Hao, Fan Zhuangzhuang, Archives of Oral Biology . 2019 ,第期

机译：BMP4牙齿血肿和低骨质量突变
2. Association of BMP4 polymorphisms with isolated tooth agenesis in a Chinese Han population: a case-control study [J] . Gong M., Qian Y. -J., Gu N., European review for medical and pharmacological sciences. . 2015 ,第12期

机译：BMP4基因多态性与中国汉族人群孤立牙发育不良的关联：病例对照研究
3. Association of BMP4 polymorphisms with isolated tooth agenesis in a Chinese Han population: a case-control study [J] . M. Gong, Y.-J. Qian, N. Gu, European review for medical and pharmacological sciences. . 2015 ,第12期

机译：BMP4基因多态性与中国汉族人群孤立牙发育不良的关联：病例对照研究
4. 3D Regional Differentiated Bone Remodeling Monitoring at the Proximal Femur Before, During 60 Days Bed Rest and One Year Follow-up After Using Reactive Jump Exercises as Countermeasure for Avoiding Loss of Bone Mass [C] . Zully Ritter, Daniel Belavy, Ulf Gast, International Astronautical Congress . 2019

机译：3D在近端股骨之前的区域差异化骨改造监测，在60天卧床休息期间，使用反应跳跃锻炼后的一年随访，以避免骨量丧失
5. Effect of Healing Time on New Bone Formation Following Tooth Extraction and Ridge Preservation with Demineralized Freeze-Dried Bone Allograft [D] . Whetman, Jeremiah. 2016

机译：脱钙冻干同种异体骨修复牙齿后愈合时间对新骨形成的影响
6. BMP4 mutations in tooth agenesis and low bone mass [O] . Miao Yu, Hao Wang, Zhuangzhuang Fan, -1

机译：牙齿发育不全和低骨量中的BMP4突变
7. Functional evaluation of a novel tooth agenesis-associated bone morphogenetic protein 4 prodomain mutation [O] . Yanyu Huang, Yongbo Lu, Gabriele Mues, 2013

机译：新型牙齿血液生物学相关骨形态发生蛋白4的功能性评价

BMP4 mutations in tooth agenesis and low bone mass

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