Allopurinol dose escalation to achieve serum urate below 6 mg/dL: an open-label extension study

Stamp Lisa K.; Chapman Peter T.; Barclay Murray; Horne Anne; Frampton Christopher; Tan Paul; Drake Jill; Dalbeth Nicola

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Allopurinol dose escalation to achieve serum urate below 6 mg/dL: an open-label extension study

机译：Allopurinol剂量升级以实现血清尿酸盐低于6 Mg / DL：开放标签扩展研究

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Objectives To determine the long-term safety and efficacy of allopurinol dose escalation (DE) to achieve target serum urate (SU) in gout.

机译：目的，以确定Allopurinol剂量升级（DE）在痛风中实现靶血清尿酸盐（SU）的长期安全性和疗效。

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来源
《Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research》 |2017年第12期|共6页
作者
Stamp Lisa K.; Chapman Peter T.; Barclay Murray; Horne Anne; Frampton Christopher; Tan Paul; Drake Jill; Dalbeth Nicola;
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作者单位

Univ Otago Dept Med POB 4345 Christchurch New Zealand;

Christchurch Hosp Dept Rheumatol Immunol &

Allergy Christchurch New Zealand;

Univ Otago Dept Med POB 4345 Christchurch New Zealand;

Univ Auckland Dept Med Auckland New Zealand;

Univ Otago Dept Med POB 4345 Christchurch New Zealand;

Univ Auckland Dept Med Auckland New Zealand;

Univ Otago Dept Med POB 4345 Christchurch New Zealand;

Univ Auckland Dept Med Auckland New Zealand;

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原文格式 PDF
正文语种 eng
中图分类免疫性疾病;
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专利

1. Allopurinol dose escalation to achieve serum urate below 6 mg/dL: an open-label extension study [J] . Stamp Lisa K., Chapman Peter T., Barclay Murray, Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research . 2017,第12期

机译：Allopurinol剂量升级以实现血清尿酸盐低于6 Mg / DL：开放标签扩展研究
2. Effects of Allopurinol Dose Escalation on Bone Erosion and Urate Volume in Gout: A Dual‐Energy Computed Tomography Imaging Study Within a Randomized, Controlled Trial [J] . Dalbeth Nicola, Billington Karen, Doyle Anthony, Arthritis & rheumatology. . 2019,第10期

机译：Allopurinol剂量升级对痛风中骨腐蚀和尿液施用的影响：随机，对照试验中的双能计算断层摄影成像研究
3. An Open-Label Dose-Finding Study of Allopurinol to Target Defined Reduction in Urate Levels in Hemodialysis Patients [J] . Rutherford Elaine, Stewart Graham, Houston J. Graeme, The Journal of Clinical Pharmacology: Official Journal of the American College of Clinical Pharmacology . 2017,第11期

机译：Allopurinol对血液透析患者尿液水平的靶向减少的开放式剂量调查研究
4. Pharmacokinetic and bioequivalencecomparison between capsule and conventionaltablet formulations of paeonol: an open-label,single-dose, randomized-sequence,two-period crossover study in healthyChinese male volunteers [C] . Jianheng Li, Xinghong Zhang, Lifeng Hou, International Conference on Human Health and Medical Engineering. . 2014

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5. A phase I study of vincristine, escalating doses of irinotecan, temozolomide and bevacizumab (VIT-B) in pediatric and adolescent patients with recurrent or refractory solid tumors of non-hematopoietic origin [D] . Venkatramani, Rajkumar. 2010

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7. An open-label dose-finding study of allopurinol to target defined reduction in urate levels in hemodialysis patients [O] . Rutherford Elaine, Stewart Graham, Houston J. Graeme, 2017

机译：一项针对别嘌呤醇的开放标签剂量发现研究，旨在确定血液透析患者尿酸盐水平的降低

Allopurinol dose escalation to achieve serum urate below 6 mg/dL: an open-label extension study

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