Tumor-Specific Labeling of Pancreatic Cancer Using a Humanized Anti-CEA Antibody Conjugated to a Near-Infrared Fluorophore

Lwin Thinzar M.; Murakami Takashi; Miyake Kentaro; Yazaki Paul J.; Shivley John E.; Hoffman Robert M.; Bouvet Michael

首页> 外文期刊>Annals of surgical oncology >Tumor-Specific Labeling of Pancreatic Cancer Using a Humanized Anti-CEA Antibody Conjugated to a Near-Infrared Fluorophore

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Tumor-Specific Labeling of Pancreatic Cancer Using a Humanized Anti-CEA Antibody Conjugated to a Near-Infrared Fluorophore

机译：使用与近红外荧光团缀合的人源化抗CEA抗体的肿瘤特异性标记胰腺癌

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Development of a humanized fluorophore-conjugated antibody that can improve contrast for fluorescence-guided oncologic surgeries.

机译：荧光团共轭抗体的研制可以改善荧光引导的肿瘤手术的对比度。

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来源
《Annals of surgical oncology》 |2018年第4期|共7页
作者
Lwin Thinzar M.; Murakami Takashi; Miyake Kentaro; Yazaki Paul J.; Shivley John E.; Hoffman Robert M.; Bouvet Michael;
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作者单位

Univ Calif San Diego Dept Surg San Diego CA 92103 USA;

Univ Calif San Diego Dept Surg San Diego CA 92103 USA;

Univ Calif San Diego Dept Surg San Diego CA 92103 USA;

City Hope Natl Med Ctr 1500 E Duarte Rd Duarte CA 91010 USA;

City Hope Natl Med Ctr 1500 E Duarte Rd Duarte CA 91010 USA;

Univ Calif San Diego Dept Surg San Diego CA 92103 USA;

Univ Calif San Diego Dept Surg San Diego CA 92103 USA;

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原文格式 PDF
正文语种 eng
中图分类外科学;
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专利

1. Tumor-Specific Labeling of Pancreatic Cancer Using a Humanized Anti-CEA Antibody Conjugated to a Near-Infrared Fluorophore [J] . Lwin Thinzar M., Murakami Takashi, Miyake Kentaro, Annals of surgical oncology . 2018,第4期

机译：使用与近红外荧光团缀合的人源化抗CEA抗体的肿瘤特异性标记胰腺癌
2. Fluorophore-conjugated anti-CEA antibody for the intraoperative imaging of pancreatic and colorectal cancer. [J] . Kaushal S, McElroy MK, Luiken GA, Journal of gastrointestinal surgery: official journal of the Society for Surgery of the Alimentary Tract . 2008,第11期

机译：荧光素偶联的抗CEA抗体用于胰腺癌和大肠癌的术中成像。
3. Successful fluorescence-guided surgery on human colon cancer patient-derived orthotopic xenograft mouse models using a fluorophore-conjugated anti-CEA antibody and a portable imaging system [J] . HiroshimaY., MaawyA., MetildiC.A., Journal of laparoendoscopic and advanced surgical techniques, Part A . 2014,第4期

机译：使用荧光团偶联的抗CEA抗体和便携式成像系统对人结肠癌患者原位异种移植小鼠模型进行成功的荧光引导手术
4. Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model [C] . Thinzar M. Lwin, Kentaro Miyake, Takashi Murakami, Molecular-Guided Surgery: Molecules, Devices, and Applications IV . 2018

机译：荧光人源化抗CEA抗体在源自患者的原位异种移植（PDOX）小鼠模型中特异性标记转移性胰腺癌
5. Harnessing Antibodies for Treating Pancreatic Cancer: AR9.6 a MUC16 Specific Monoclonal Antibody [D] . Aguilar, Eric Nunez. 2021

机译：用于治疗胰腺癌的抗体：AR9.6 A型MUC16特异性单克隆抗体
6. Tumor-specific labeling of pancreatic cancer using a humanized anti-CEA antibody conjugated to a near-infrared fluorophore [O] . Thinzar M. Lwin, Takashi Murakami, Kentaro Miyake, -1

机译：使用与近红外荧光团偶联的人源化抗CEA抗体对胰腺癌进行肿瘤特异性标记
7. Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model [O] . Thinzar M. Lwin, Kentaro Miyake, Takashi Murakami, 2018

机译：荧光人源化抗CEA抗体特异性标记患者衍生的原位异种移植物（PDOX）小鼠模型中的转移性胰腺癌

Tumor-Specific Labeling of Pancreatic Cancer Using a Humanized Anti-CEA Antibody Conjugated to a Near-Infrared Fluorophore

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