QUESTION 1What is the risk of a repeat reaction to amoxicillin or a cephalosporin in children with a history of a non-immediate reaction to amoxicillin?

摘要

SCENARIO You are looking after a previously well 4-year-old girl who presents with right ear pain and fever. You diagnose her with otitis media and are about to prescribe her amoxicillin when her parents show you a photo of an urticarial rash that she developed 6 hours after a previous dose of amoxicillin. When counselling the parents you wonder what the risk is of a repeat reaction to (i) amoxicillin or (ii) a cephalosporin?