2,3-Dichloro-5,6-Dicyano-1,4-Benzoquinone (DDQ)-Mediated Tandem Oxidative Coupling/Intramolecular Annulation/Dehydro-Aromatization for the Synthesis of Polysubstituted and Fused Pyridines

摘要

A DDQ-mediated tandem reaction of 1,3-diarylpropenes and beta-enaminoesters/4-aminocoumarins is disclosed. It involves oxidative coupling, intramolecular annulation and dehydro-aromatization reaction, which provides an efficient and mild method for the synthesis of polysubstituted and fused pyridines under metal-free conditions.