Heme Oxygenase-1 Upregulation: A Novel Approach in the Treatment of Cardiovascular Disease

Bellner Lars; Lebovics Nachum B.; Rubinstein Rochelle; Buchen Yosef D.; Sinatra Emilia; Sinatra Giuseppe; Abraham Nader G.; McClung John A.; Thompson Ellen A.

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Heme Oxygenase-1 Upregulation: A Novel Approach in the Treatment of Cardiovascular Disease

机译：血红素氧合酶-1上调：一种治疗心血管疾病的新方法

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Recent Advances: From the regulation of adipogenesis in adipose tissue to the adaptive response of vascular tissue in the ECs, HO plays a critical role in the capability of the vascular system to respond and adjust to insults in homeostasis. Recent studies show that HO-1 through regulation of adipocyte and adipose tissue functions ultimately aid not only in local but also in systemic maintenance of homeostasis.

机译：最近的进展：从脂肪组织中的脂肪发生调节到ECS中血管组织的适应性响应，HO在血管系统的能力中发挥着关键作用，以应对和调整稳态性的侮辱。最近的研究表明，HO-1通过调节脂肪细胞和脂肪组织功能最终不仅在局部的局部辅助，而且还可以在稳态的全身维持中辅助。

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来源
《Antioxidants and redox signalling》 |2020年第14期|共16页
作者
Bellner Lars; Lebovics Nachum B.; Rubinstein Rochelle; Buchen Yosef D.; Sinatra Emilia; Sinatra Giuseppe; Abraham Nader G.; McClung John A.; Thompson Ellen A.;
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作者单位

New York Med Coll Dept Pharmacol Valhalla NY 10595 USA;

New York Med Coll Dept Pharmacol Valhalla NY 10595 USA;

New York Med Coll Dept Pharmacol Valhalla NY 10595 USA;

New York Med Coll Dept Pharmacol Valhalla NY 10595 USA;

New York Med Coll Dept Pharmacol Valhalla NY 10595 USA;

New York Med Coll Dept Pharmacol Valhalla NY 10595 USA;

New York Med Coll Dept Pharmacol Valhalla NY 10595 USA;

New York Med Coll Dept Med Valhalla NY 10595 USA;

Marshall Univ Joan C Edwards Sch Med Dept Med Huntington WV USA;

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原文格式 PDF
正文语种 eng
中图分类基础医学;
关键词
heme oxygenase; obesity; adipocytes; cardiovascular disease; oxidative stress;

机译：血红素氧气;肥胖;脂肪细胞;心血管疾病;氧化应激;

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专利

1. Heme Oxygenase-1 Upregulation: A Novel Approach in the Treatment of Cardiovascular Disease [J] . Bellner Lars, Lebovics Nachum B., Rubinstein Rochelle, Antioxidants and redox signalling . 2020,第14期

机译：血红素氧合酶-1上调：一种治疗心血管疾病的新方法
2. Genetic variants of the promoter of the heme oxygenase-1 gene and their influence on cardiovascular disease (The Ludwigshafen Risk and Cardiovascular Health Study) [J] . Nicola Lüblinghoff, Karl Winkler, Bernhard R Winkelmann, BMC Medical Genetics . 2009,第1期

机译：血红素加氧酶-1基因启动子的遗传变异及其对心血管疾病的影响（路德维希港风险和心血管健康研究）
3. Therapeutic Roles of Heme Oxygenase-1 in Metabolic Diseases: Curcumin and Resveratrol Analogues as Possible Inducers of Heme Oxygenase-1 [J] . YongSon, Ju HwanLee, Hun-TaegChung, Oxidative Medicine and Cellular Longevity . 2013,第6期

机译：血红素加氧酶-1在代谢性疾病中的治疗作用：姜黄素和白藜芦醇类似物可能是血红素加氧酶-1的诱导剂
4. Development of Extracorporeal Shock Wave Therapy for the Treatment for Ischemic Cardiovascular Diseases [C] . Hiroaki Shimokawa International Symposium on Shock Waves . 2015

机译：体外冲击波疗法在缺血性心血管疾病治疗中的发展
5. The Value of Novel Antihyperlipidemic Treatments in the U.S. Healthcare System: Reducing the Burden of Cardiovascular Diseases and Filling the Gap of Low Adherence in Statins [D] . Cheng, Wei-Han. 2018

机译：美国医疗保健系统新型抗高兴血微血症的价值：降低心血管疾病的负担，填补他汀类药物的低粘附性差距
6. Heme Oxygenase-1 Upregulation: A Novel Approach in the Treatment of Cardiovascular Disease [O] . Lars Bellner, Nachum B. Lebovics, Rochelle Rubinstein, -1

机译：血红素加氧酶-1上调：一种治疗心血管疾病的新方法
7. Therapeutic Roles of Heme Oxygenase-1 in Metabolic Diseases: Curcumin and Resveratrol Analogues as Possible Inducers of Heme Oxygenase-1 [O] . Yong Son, Ju Hwan Lee, Hun-Taeg Chung, 2013

机译：血红素氧合酶-1在代谢疾病中的治疗作用：姜黄素和白藜芦醇类似物，作为血红素氧酶-1可能的诱导剂
8. Targeted Upregulation of FMRP Expression as an Approach to the Treatment of Fragile X Syndrome. [R] . Hagerman, P. 2016

机译：针对FmRp表达的靶向上调作为治疗脆性X综合征的一种方法。

Heme Oxygenase-1 Upregulation: A Novel Approach in the Treatment of Cardiovascular Disease

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