Change in prepregnancy body mass index and gastroschisis

摘要

Purpose: Maternal body mass index (BMI) is inversely associated with gastroschisis, but a causal relationship has not been established. As data demonstrating that a change in exposure status is related to a change in the frequency of the outcome can add to the evidence for causality, we conducted a case -control study of change in maternal BMI, assessed using interpregnancy change in BMI (IPC-BMI), and gastroschisis.