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An experimental study: quantitatively evaluating the change of the content of collagen fibres in penis with two-dimensional ShearWave (TM) Elastography

机译:实验研究:定量评估阴茎胶原纤维含量的变化,具有二维避难所的弹性术

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摘要

The purpose of this study was to explore the value of two-dimensional ShearWave Elastography (2D-SWE) on quantitatively evaluating the change of the content of collagen fibres in penis. Twenty male Sprague Dawley rats were divided into the pre-sexual maturity group (Group 1) and the sexual decline group (Group 2) according to age. The ultrafast ultrasound device Aixplorer((R)) (SuperSonic Imagine, Aix-en-Provence, France) was used for 2D-SWE imaging of penis, and the measurement index was shear wave stiffness (SWS). The immunohistochemistry was used to analyse the content of collagen fibres in penis, and the measurement index was positive area percentage (PAP). The differences of SWS between the two groups and PAP between the two groups were analysed. SWS of Group 1 and Group 2 was 10.18 +/- 1.09 and 8.02 +/- 1.34kPa, and SWS of Group 2 was significantly lower than Group 1 (p<.01). PAP of Group 1 and Group 2 was 4.83 +/- 3.61% and 16.41 +/- 10.02%, and PAP of Group 2 was significantly higher than Group 1 (p<.01). Our results indicate that when the content of collagen fibres changes, SWS of penis measured with 2D-SWE would change significantly as well. Two-dimensional SWE can be used to quantitatively evaluate the change of the content of collagen fibres in penis.
机译:本研究的目的是探讨二维剪切波弹性摄影(2D-SWE)的值,以定量评估阴茎中胶原纤维含量的变化。 20名雄性Sprague Dawley大鼠分为性预期组(第1组)和性衰退组(第2组)根据年龄。超快超声设备AixPlorer((R))(超音速拍摄,AIX-in普罗旺斯,法国)用于阴茎的2D-SWE成像,测量指数是剪切波刚度(SWS)。免疫组织化学用于分析阴茎中胶原纤维的含量,测量指数为阳性面积百分比(PAP)。分析了两组之间的SWS与两组之间的毒剂之间的差异。第1组和第2组的SW是10.18 +/- 1.09和8.02 +/- 1.34kPa,第2组SWS显着低于1(P <.01)。第1组和第2组的PAP为4.83 +/- 3.61%和16.41 +/- 10.02%,第2组PAP显着高于1(P <.01)。我们的结果表明,当胶原纤维的含量发生变化时,用2D-SWE测量的阴茎SWS也会显着变化。二维SWE可用于定量评估阴茎中胶原纤维含量的变化。

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  • 来源
    《Andrologia》 |2017年第5期|共5页
  • 作者单位

    Shanghai Jiao Tong Univ Sch Med Dept Med Ultrasound Shanghai Gen Hosp Shanghai Peoples R China;

    Shanghai Jiao Tong Univ Sch Med Dept Med Ultrasound Shanghai Gen Hosp Shanghai Peoples R China;

    Shanghai Jiao Tong Univ Sch Med Dept Med Ultrasound Shanghai Gen Hosp Shanghai Peoples R China;

    Shanghai Jiao Tong Univ Sch Med Dept Med Ultrasound Shanghai Gen Hosp Shanghai Peoples R China;

    Shanghai Jiao Tong Univ Sch Med Dept Med Ultrasound Shanghai Gen Hosp Shanghai Peoples R China;

    Shanghai Jiao Tong Univ Sch Med Dept Med Ultrasound Shanghai Gen Hosp Shanghai Peoples R China;

    Shanghai Jiao Tong Univ Sch Med Dept Med Ultrasound Shanghai Gen Hosp Shanghai Peoples R China;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 男性生殖器疾病;
  • 关键词

    collagen fibres; immunohistochemistry; penis; shear wave stiffness; two-dimensional ShearWave (TM) Elastography;

    机译:胶原纤维;免疫组化;阴茎;剪切波刚度;二维避难所(TM)弹性造影;

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