Heart dose exposure as prognostic marker after radiotherapy for resectable stage IIIA/B non-small-cell lung cancer: secondary analysis of a randomized trial

Guberina M.; Eberhardt W.; Stuschke M.; Gauler T.; Heinzelmann F.; Cheufou D.; Kimmich M.; Friedel G.; Schmidberger H.; Darwiche K.; Jendrossek V.; Schuler M.; Stamatis G.; Pottgen C.

首页> 外文期刊>Annals of oncology: official journal of the European Society for Medical Oncology >Heart dose exposure as prognostic marker after radiotherapy for resectable stage IIIA/B non-small-cell lung cancer: secondary analysis of a randomized trial

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Heart dose exposure as prognostic marker after radiotherapy for resectable stage IIIA/B non-small-cell lung cancer: secondary analysis of a randomized trial

机译：心脏剂量暴露作为预后标志物放射治疗，可重新切除阶段IIIA / B非小细胞肺癌：随机试验的二次分析

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Background: Heart exposure to ionizing irradiation can cause ischaemic heart disease. The partial heart volume receiving >= 5 Gy (heartV5) was supposed to be an independent prognostic factor for survival after radiochemotherapy for locally advanced non-small-cell lung cancer (NSCLC). But validation of the latter hypothesis is needed under the concurrent risks of lung cancer patients.

机译：背景：心脏暴露在电离辐照中会导致缺血性心脏病。接受部分心脏体积> = 5 GY（HeartV5）应该是对局部晚期非小细胞肺癌（NSCLC）进行放射性化疗后存活的独立预后因素。但是，在肺癌患者的同时风险下需要验证后一种假设。

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来源
《Annals of oncology: official journal of the European Society for Medical Oncology》 |2017年第5期|共6页
作者
Guberina M.; Eberhardt W.; Stuschke M.; Gauler T.; Heinzelmann F.; Cheufou D.; Kimmich M.; Friedel G.; Schmidberger H.; Darwiche K.; Jendrossek V.; Schuler M.; Stamatis G.; Pottgen C.;
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作者单位

Univ Duisburg Essen Univ Hosp Essen West German Canc Ctr Dept Radiat Oncol Essen Germany;

Univ Duisburg Essen Univ Hosp Essen West German Canc Ctr Dept Med Oncol Essen Germany;

Univ Duisburg Essen Univ Hosp Essen West German Canc Ctr Dept Radiat Oncol Essen Germany;

Univ Duisburg Essen Univ Hosp Essen West German Canc Ctr Dept Radiat Oncol Essen Germany;

Univ Tubingen Dept Radiat Oncol Tubingen Germany;

Univ Hosp Essen Ruhrlandklin Dept Thorac Surg Essen Germany;

Robert Bosch Krankenhaus Klinikum Schillerhohe Dept Pulmonol Gerlingen Germany;

Robert Bosch Krankenhaus Klinikum Schillerhohe Dept Thorac Surg Gerlingen Germany;

Univ Hosp Mainz Dept Radiotherapy Mainz Germany;

Ruhrlandklinik Dept Pulmonol Essen Germany;

Univ Duisburg Essen Inst Cell Biol Canc Res Essen Germany;

Univ Duisburg Essen Univ Hosp Essen West German Canc Ctr Dept Med Oncol Essen Germany;

Univ Hosp Essen Ruhrlandklin Dept Thorac Surg Essen Germany;

Univ Duisburg Essen Univ Hosp Essen West German Canc Ctr Dept Radiat Oncol Essen Germany;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词
heart dose; prognostic factor; radiotherapy; concurrent chemotherapy; lung cancer;

机译：心脏剂量;预后因子;放射疗法;同时化疗;肺癌;

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专利

1. Heart dose exposure as prognostic marker after radiotherapy for resectable stage IIIA/B non-small-cell lung cancer: secondary analysis of a randomized trial [J] . Guberina M., Eberhardt W., Stuschke M., Annals of oncology: official journal of the European Society for Medical Oncology . 2017,第5期

机译：心脏剂量暴露作为预后标志物放射治疗，可重新切除阶段IIIA / B非小细胞肺癌：随机试验的二次分析
2. Prognostic Value of Metabolic Tumor Volume after Induction Chemotherapy in Stage IIIA/B Non-Small-Cell Lung Cancer - Secondary Analysis of a Randomized Phase 3 Trial [J] . Guberina M., Stuschke M., Eberhardt W., International Journal of Radiation Oncology, Biology, Physics . 2019,第1Suppla期

机译：IIIA / B非小细胞肺癌型诱导化疗后代谢肿瘤体积的预后价值 - 随机阶段3试验的二次分析
3. Randomized study of chemotherapy and surgery versus radiotherapy for stage IIIA non-small-cell lung cancer: a National Cancer Institute of Canada Clinical Trials Group Study [J] . FA Shepherd, MR Johnston, D Payne, British Journal of Cancer . 1998,第5期

机译：IIIA期非小细胞肺癌化学疗法，手术疗法与放射疗法的随机对照研究：加拿大国家癌症研究所临床试验小组研究
4. CT image fusion in the optimization of replanning during the course of 3-dimensional conformal radiotherapy for non-small-cell lung cancer [C] . Xu XiMing, Deng JunJian, Guo HongTing, 2010 3rd International Conference on Biomedical Engineering and Informatics . 2010

机译：非小细胞肺癌3D立体适形放疗过程中CT图像融合对重新计划的优化
5. Subgroup analysis based on prognostic and predictive gene signatures for adjuvant chemotherapy in early-stage non-small-cell lung cancer patients [D] . Pluta, Dustin. 2015

机译：基于预后和预测基因特征的亚组分析用于早期非小细胞肺癌患者的辅助化疗
6. Standard-dose versus high-dose conformal radiotherapy with concurrent and consolidation carboplatin plus paclitaxel with or without cetuximab for patients with stage IIIA or IIIB non-small-cell lung cancer (RTOG 0617): a randomised two-by-two factorial phase 3 study [O] . Prof. Jeffrey D Bradley, Rebecca Paulus, Prof. Ritsuko Komaki, -1

机译：IIIA期或IIIB期非小细胞肺癌（RTOG 0617）患者的标准剂量与大剂量适形放疗联合或合并卡铂联合紫杉醇联合西妥昔单抗联合或不联合西妥昔单抗研究
7. Prognostic Value of Metabolic Tumor Volume after Induction Chemotherapy in Stage IIIA/B Non-Small-Cell Lung Cancer – Secondary Analysis of a Randomized Phase 3 Trial [O] . M. Guberina, M. Stuschke, W. Eberhardt, 2019

机译：IIIA / B非小细胞肺癌型诱导化疗后代谢肿瘤体积的预后价值 - 随机阶段3试验的二次分析

Heart dose exposure as prognostic marker after radiotherapy for resectable stage IIIA/B non-small-cell lung cancer: secondary analysis of a randomized trial

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