Synergy Assessment of Hypoxia and Lipopolysaccharide on Autophagy in Dendritic Cells

摘要

OBJECTIVE: In hypoxia, the most common mechanism of injury is the increase in reactive oxygen species and energy deficiency, which can cause mitochondrial morphology and endogenous apoptosis. This study investigated whether autophagy was activated by a large number of active regulatory processes to adapt cells to hypoxia and help protect against hypoxia. Additionally, the role of lipopolysaccharide (LPS) in this process was assessed.