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Detection of Potentially Toxic Additives in Electronic Cigarettes and Cigarette Flavourings

机译:检测电子烟和香烟调味品中潜在有毒添加剂

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摘要

While the popularity of electronic cigarettes (e-cigarettes) has rapidly increased in recent years, the regulation around the composition of such e-cigarettes has lagged. Many components of the e-cigarettes and liquid flavorings (e-liquids) used in these products are not disclosed, and the potential for exposure to toxic compounds via use of these products is significant. Reported herein is an analysis of the components of e-cigarettes as well as of three popular e-liquids via gas chromatography – mass spectrometry. These results show that components of the e-cigarette contain large quantities of aromatic compounds, and that the e-liquids contain smaller quantities of potentially concerning additives. Most notably, 96% of the extract from the filter was composed of benzyl chloride, a potent DNA alkylating agent, a result which should be of significant concern to consumers, regulatory agencies, and e-cigarette manufacturers.
机译:虽然近年来电子烟头(电子卷烟)的普及迅速增加,但这些电子烟的组成周围的调节已经滞后。 本产品中使用的电子香烟和液体调味剂(E-液体)的许多组分未公开,并且通过使用这些产品暴露于有毒化合物的可能性是显着的。 本文报道的是通过气相色谱 - 质谱法对e-卷烟的组分以及三种普遍的E-液体分析。 这些结果表明,电子香烟的组分含有大量的芳族化合物,并且E-液体含有较小的潜在的添加剂。 值得注意的是,96%的过滤器中的提取物由苄基氯,效力DNA烷基化剂组成,结果应该对消费者,监管机构和电子卷烟制造商具有重要关注。

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