Electrochemical Determination of Uric Acid Using a Multiwalled Carbon Nanotube Platinum-Nickel Alloy Glassy Carbon Electrode

摘要

Platinum-nickel nanoparticles were synthesized by a reduction procedure. The Pt-Ni/C composite was characterized by X-ray diffraction, infrared spectroscopy, transmission electron microscopy, and electrochemical analysis. The measurements show that the Pt-Ni/multiwalled carbon nanotubes provided higher electrocatalytic activity for the oxidation of uric acid than Pt-Ni/carbon black. The sensor prepared from the characterized material provided a long linear dynamic range from 0.1 to 240.4 mu M with a detection limit of 0.03 mu M and a sensitivity of 41.21 mu AmM(-1)cm(-2). The reported modified electrode also provided excellent selectivity, good stability, and satisfactory reproducibility for the determination of uric acid.