Ketamine and Etomidate Down-regulate the Hypothalamic-Pituitary-Adrenal Axis in an Endotoxemic Mouse Model

Besnier Emmanuel; Clavier Thomas; Tonon Marie-Christine; Selim Jean; Lefevre-Scelles Antoine; Morin Fabrice; Tamion Fabienne; Dureuil Bertrand; Castel Helene; Compere Vincent

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Ketamine and Etomidate Down-regulate the Hypothalamic-Pituitary-Adrenal Axis in an Endotoxemic Mouse Model

机译：氯胺酮和膦酸酯下调内毒性小鼠模型中的下丘脑 - 垂体 - 肾上腺轴

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Background: We compared the effects of etomidate and ketamine on the hypothalamic-pituitary-adrenal axis during sepsis.

机译：背景：在败血症期间，我们比较了依托咪啶亚胺和氯胺酮对下丘脑 - 垂体肾上腺轴的影响。

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《Anesthesiology》 |2017年第2期|共8页
作者
Besnier Emmanuel; Clavier Thomas; Tonon Marie-Christine; Selim Jean; Lefevre-Scelles Antoine; Morin Fabrice; Tamion Fabienne; Dureuil Bertrand; Castel Helene; Compere Vincent;
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作者单位

UNIROUEN Rouen Univ Rouen Univ Hosp Normandy Univ Dept Anesthesia &

Crit Care Rouen France;

UNIROUEN Rouen Univ Rouen Univ Hosp Normandy Univ Dept Anesthesia &

Crit Care Rouen France;

UNIROUEN Normandy Univ Lab Neuronal &

Neuroendocrine Differentiat &

Comm INSERM U982 Rouen;

UNIROUEN Rouen Univ Rouen Univ Hosp Normandy Univ Dept Anesthesia &

Crit Care Rouen France;

UNIROUEN Rouen Univ Rouen Univ Hosp Normandy Univ Dept Anesthesia &

Crit Care Rouen France;

UNIROUEN Normandy Univ Lab Neuronal &

Neuroendocrine Differentiat &

Comm INSERM U982 Rouen;

UNIROUEN Rouen Univ Rouen Univ Hosp Normandy Univ Med Crit Care Unit Rouen France;

UNIROUEN Rouen Univ Rouen Univ Hosp Normandy Univ Dept Anesthesia &

Crit Care Rouen France;

UNIROUEN Normandy Univ Lab Neuronal &

Neuroendocrine Differentiat &

Comm INSERM U982 Rouen;

UNIROUEN Rouen Univ Rouen Univ Hosp Normandy Univ Dept Anesthesia &

Crit Care Rouen France;

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正文语种 eng
中图分类麻醉学;
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1. Ketamine and Etomidate Down-regulate the Hypothalamic-Pituitary-Adrenal Axis in an Endotoxemic Mouse Model [J] . Besnier Emmanuel, Clavier Thomas, Tonon Marie-Christine, Anesthesiology . 2017,第2期

机译：氯胺酮和膦酸酯下调内毒性小鼠模型中的下丘脑 - 垂体 - 肾上腺轴
2. Progressive alterations in the hypothalamic-pituitary-adrenal axis in the R6/2 transgenic mouse model of Huntington's disease. [J] . Bjorkqvist M, Petersen A, Bacos K, Human Molecular Genetics . 2006,第10期

机译：在亨廷顿舞蹈病的R6 / 2转基因小鼠模型中，下丘脑-垂体-肾上腺轴的进行性改变。
3. Progressive alterations in the hypothalamic-pituitary-adrenal axis in the R6/2 transgenic mouse model of Huntington's disease [J] . Maria Björkqvist, Åsa Petersén, Karl Bacos, Human Molecular Genetics . 2006,第10期

机译：亨廷顿舞蹈病R6 / 2转基因小鼠模型的下丘脑-垂体-肾上腺轴进行性改变
4. Immunology, Signal Transduction, and Behavior in Hypothalamic-Pituitary-Adrenal Axis-related Genetic Mouse Models [C] . Susana Silberstein, Annette M. Vogl, Juan Jose Bon.figlio, International Society for Neuroimmunomodulation . 2009

机译：丘脑 - 垂体肾上腺轴相关遗传小鼠模型中的免疫学，信号转导和行为
5. Negative feedback control over the hypothalamic-pituitary-adrenal axis response to stress is a function of temporal, spatial and physiological actions of corticosterone. [D] . Osterlund, Chad Donahue. 2013

机译：下丘脑-垂体-肾上腺轴对压力反应的负反馈控制是皮质酮的时间，空间和生理作用的函数。
6. A Comparison of Ketamine or Etomidate Combined with Xylazine for Intraperitoneal Anesthesia in Four Mouse Strains [O] . Crystal H Gergye, Yixuan Zhao, Reneé H Moore, 2020

机译：在四种小鼠菌株中对氯胺酮或依赖噻嗪与甲嗪联合腹膜内麻醉的比较
7. Progressive alterations in the hypothalamic-pituitary-adrenal axis in the R6/2 transgenic mouse model of Huntington's disease [O] . Maria Björkqvist, Åsa Petersén, Karl Bacos, 2006

机译：Huntington疾病R6 / 2转基因小鼠模型中下丘脑 - 垂体 - 肾上腺轴的渐进式改变

Ketamine and Etomidate Down-regulate the Hypothalamic-Pituitary-Adrenal Axis in an Endotoxemic Mouse Model

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