首页> 外文期刊>American Journal of Ophthalmology: The International Journal of Ophthalmology >Aqueous Humor Analysis Identifies Higher Branched Chain Amino Acid Metabolism as a Marker for Human Leukocyte Antigen-B27 Acute Anterior Uveitis and Disease Activity
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Aqueous Humor Analysis Identifies Higher Branched Chain Amino Acid Metabolism as a Marker for Human Leukocyte Antigen-B27 Acute Anterior Uveitis and Disease Activity

机译:幽默分析鉴定了较高的分支链氨基酸代谢作为人白细胞抗原-B27急性前葡萄膜炎和疾病活性的标志物

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PURPOSE: Human leukocyte antigen-B27 (HLA-B27)-positive acute anterior uveitis (AAU) has a higher recurrence rate and shows more anterior chamber cell infiltration compared with HLA-B27-negative patients, suggesting distinct etiologies of these clinically overlapping conditions. To advance our understanding of the biology of AAU, we characterized the metabolic profile of aqueous humor (AqH) of patients with HLA-B27-associated AAU (B27-AAU) and noninfectious idiopathic AAU (idiopathic AAU).
机译:目的:人白细胞抗原-B27(HLA-B27) - 阳性急性前葡萄炎(AAU)具有更高的复发率,并且与HLA-B27阴性患者相比,更高的前室细胞浸润,表明这些临床重叠条件的不同病因。 为了推进我们对AAU生物学的理解,我们表征了HLA-B27相关AAU(B27-AAU)和非排感性发作性AAU(特发性AAU)的患者水性幽默(AQH)的代谢剖面。

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