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首页> 外文期刊>American Journal of Ophthalmology: The International Journal of Ophthalmology >Outcomes and Predictive Factors After Cataract Surgery in Patients With Neovascular Age-related Macular Degeneration. The Fight Retinal Blindness! Project
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Outcomes and Predictive Factors After Cataract Surgery in Patients With Neovascular Age-related Macular Degeneration. The Fight Retinal Blindness! Project

机译:新生血管年龄相关黄斑变性患者白内障手术后的结果和预测因素。 抗击视网膜失明! 项目

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PurposeTo evaluate outcomes and predictive factors of visual acuity (VA) change after cataract surgery in patients being treated for neovascular age-related macular degeneration (nAMD). DesignRetrospective, matched case-control study. MethodsWe studied eyes undergoing cataract surgery that had been tracked since they first started treatment for nAMD. These eyes were compared with a cohort of unoperated phakic eyes being treated for nAMD (3 per case) matched for treatment duration before cataract surgery, baseline VA, age, and length of follow-up. ResultsWe included 124 patients that had cataract surgery and 372 matched controls. The mean (95% confidence interval) VA gained was 10.6 letters (7.8, 13.2;P?
机译:Purposeto评估视力(VA)的结果和预测因素在治疗新生血管年龄相关性黄斑变性(NAMD)后的白内障手术后的变化。 DesignRetrospive,匹配案例对照研究。方法网络研究了曾经被追踪的白内障手术,因为他们首先开始对NAMD进行治疗。将这些眼睛与被用于治疗持续时间的NAMD(3每种情况)治疗的未手术的Phakic眼睛群体进行比较,以进行白内障手术,基线VA,年龄和随访时间。 Resultswe包括124名患者,具有白内障手术和372名匹配对照。所获得的平均值(95%置信区间)VA为10.6个字母(7.8,13.2; p?<β.001)12?手术后的月份; 26.0%已获得≥3条线,1.6%损失了≥3行的VA。视力(平均值[标准偏差])12?手术后的几个月在具有白内障萃取的眼睛中较高,与对照相比脉络膜新生血管(CNV)病变被渐变的探析活性的比例和手术前后类似的注射次数(p?= .506 andp?= .316),而对照组减少,建议手术适度增加了CNV病变的活性水平。在手术前的意思是[SD] VA在眼睛中较低,与获得0-14个字母的眼睛相比≥15个字母(40.2 [21.4] Vs 62.1 [15.1],p≤001)。在前6个月内接受白内障手术的患者抗VEGF治疗的可能性更可能失去而不是获得视觉(20.8%的视觉损失与12.8%和4.4%,分别获得≥15或0-14字母,p?= .023 )。年龄,在手术前至少2次接受注射,并且CNV病变型与VA结果没有可辨别的关联。结论我们发现了表达白内障手术对纳姆治疗的眼睛CNV病变活动的效果。尽管如此,视觉结果很好。如果可能,应避免在6中6?几个月内进行NAMD开始治疗。

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