Investigation on the Stability of New Biologically Active Thiosemicarbazone-Derived Compounds by a Validated HPLC-PDA Method

摘要

Background: New Chemical Entities (NCEs) could be generally exposed to several stress conditions of hydrolysis. oxidation. photolysis and thermal degradation in order to better characterize the compounds and to know if the degradation processes lead to generate undesired (or toxic) products.