Safety and Efficacy of Incretin-Based Therapies in Patients With Type 2 Diabetes Mellitus and CKD: A Systematic Review and Meta-analysis

Howse Patricia M.; Chibrikova Lyudmila N.; Twells Laurie K.; Barrett Brendan J.; Gamble John-Michael

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Safety and Efficacy of Incretin-Based Therapies in Patients With Type 2 Diabetes Mellitus and CKD: A Systematic Review and Meta-analysis

机译：基于Incetin的疗法在2型糖尿病和CKD患者中的安全性和有效性：系统评价和荟萃分析

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摘要

Background: The pharmacokinetics and pharmacodynamics of antidiabetic therapies for patients with type 2 diabetes are often altered in the context of chronic kidney disease (CKD).

机译：背景：2型糖尿病患者的抗糖尿病疗法的药代动力学和药效学常常在慢性肾脏疾病（CKD）的背景下改变。

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来源
《American Journal of Kidney Diseases: The official journal of the National Kidney Foundation 》 |2016年第5期| 共10页
作者
Howse Patricia M.; Chibrikova Lyudmila N.; Twells Laurie K.; Barrett Brendan J.; Gamble John-Michael;
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作者单位

Mem Univ Newfoundland Fac Med St John NF Canada;

Mem Univ Newfoundland Sch Pharm 300 Prince Philip Dr St John NF A1B 3V6 Canada;

Mem Univ Newfoundland Fac Med St John NF Canada;

Mem Univ Newfoundland Fac Med St John NF Canada;

Mem Univ Newfoundland Sch Pharm 300 Prince Philip Dr St John NF A1B 3V6 Canada;

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原文格式 PDF
正文语种 eng
中图分类泌尿科学（泌尿生殖系疾病） ;
关键词
Type 2 diabetes mellitus (T2DM); chronic kidney disease (CKD); systematic review; epidemiology; meta-analysis; pharmacoepidemiology; antidiabetic therapies; safety; efficacy; incretin; dipeptidyl peptidase 4 inhibitor (DPP-4); glucagon-like peptide 1 (GLP-1) receptor agonist; glycated hemoglobin (HbA(1c)); hyperglycemia;

机译：2型糖尿病（T2DM）;慢性肾病（CKD）;系统评价;流行病学;META分析;药物病疗法;抗糖尿病疗法;安全;疗效;疗效;二肽肽酶4抑制剂（DPP-4）;胰高血糖素样肽1 （GLP-1）受体激动剂;糖化血红蛋白（HBA（1C））;高血糖;

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专利

1. Safety and Efficacy of Incretin-Based Therapies in Patients With Type 2 Diabetes Mellitus and CKD: A Systematic Review and Meta-analysis [J] . Howse Patricia M., Chibrikova Lyudmila N., Twells Laurie K., American Journal of Kidney Diseases: The official journal of the National Kidney Foundation . 2016 ,第5期

机译：2型糖尿病和CKD患者以肠抑素为基础的治疗的安全性和有效性：系统评价和荟萃分析
2. Efficacy and safety of incretin-based drugs in patients with type 1 diabetes mellitus: A systematic review and meta-analysis [J] . Wang Wen, Gao Yun, Chen Dawei, Diabetes research and clinical practice . 2017 ,第期

机译：1型糖尿病患者胰素的药物疗效和安全性：系统审查和荟萃分析
3. Effect of incretin-based therapies on cancers of digestive system among 101 595 patients with type 2 diabetes mellitus: a systematic review and network meta-analysis combining 84 trials with a median duration of 30 weeks [J] . Sanbao Chai, Shuqing Yu, Zhirong Yang, BMJ Open Diabetes Research & Care . 2019 ,第1期

机译：肠降血糖素疗法对101 595例2型糖尿病患者消化系统癌症的影响：系统回顾和网络荟萃分析，结合84项试验，平均持续时间30周
4. Impact of Information Technology-Based Interventions for Type 2 Diabetes Mellitus on Glycaemic Control: a Systematic Review and Meta-Analysis [C] . NOUF ALHARBI, NAD A ALSUBKI, SIMON DE LUSIGNAN Medical Informatics in Europe Conference. . 2015

机译：基于信息技术的干预措施对血糖控制2型糖尿病的影响：系统审查和荟萃分析
5. The Efficacy of Extracorporeal Shock Wave Therapy in Comparison to Low-Level Laser Therapy for Decreasing Pain and Symptom Severity and Increasing Functional Status in Adult Patients with Carpal Tunnel Syndrome: A Systematic Review and Meta-Analysis [D] . Seely, Andrew. 2021

机译：体外冲击波治疗与低水平激光治疗对脑隧道综合征的成人患者疼痛和症状严重程度及函数状况的疗效：系统评价与荟萃分析
6. Effect of incretin-based therapies on cancers of digestive system among 101 595 patients with type 2 diabetes mellitus: a systematic review and network meta-analysis combining 84 trials with a median duration of 30 weeks [O] . Sanbao Chai, Shuqing Yu, Zhirong Yang, 2019

机译：基于肠降血糖素的疗法对101595例2型糖尿病患者消化系统癌症的影响：系统评价和网络荟萃分析结合84项试验平均持续时间30周
7. Safety and Efficacy of Incretin-Based Therapies in Patients With Type 2 Diabetes Mellitus and CKD: A Systematic Review and Meta-analysis [O] . Howse Patricia M., Chibrikova Lyudmila N., Twells Laurie K., 2016

机译：基于肠抑素的治疗2型糖尿病和CKD患者的安全性和有效性：系统评价和荟萃分析

Safety and Efficacy of Incretin-Based Therapies in Patients With Type 2 Diabetes Mellitus and CKD: A Systematic Review and Meta-analysis

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