Evaluation of the mutagenic activity of phenolics from the bark of Yucca schidigera Roezl.

摘要

The mutagenic activity of yuccaols A, B. and C. trans-resveratrol and trans - 3.3',5.5'-tetrahydroxy -4'-methoxystilbene. was tested by the Ames method with Salmonella typhimurium strains TA97, TA98, TA100, TA102 in the absence and presence of metabolic activation (S9 fraction). These phenolic compounds have been isolated and identified from the hark of Yucca schidigera. All of them were found to be non-toxic and non-mutagenic for testing doses in any of the S. typhimurium strains.