Evaluation of Different Polymers in 3D Printing Technologies

摘要

Various polymers have been investigated for 3D printing (3DP) technologies including fused deposition model, selective laser sintering, semi-solid extrusion, stereolithography and ink jet printing. The effects of additives such as plasticizing polymers/solubilizers on FDM 3DP have also been investigated. Kollidon VA 64, Soluplus, Kollidon SR, Kollicoat IR and others have been examined in pure and with plasticizing drugs or solubilizers to overcome the FDM processing conditions. The appropriate recommendations have been made to select the optimized compositions for 3DP formulation dosages. Compatibilities of polymers with other technologies requiring less stringent printing conditions, have also been evaluated. Preference of one over the other in 3DP technology could be based on the choice of excipients to yield the desired immediate or modified release profile of formulation dosages.