Differential Expression of Hedgehog and Snail in Cutaneous Fibrosing Disorders Implications for Targeted Inhibition

Goyal Amrita; Linskey Katy R.; Kay Jonathan; Duncan Lyn M.; Nazarian Rosalynn M.

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Differential Expression of Hedgehog and Snail in Cutaneous Fibrosing Disorders Implications for Targeted Inhibition

机译：针对靶向抑制的皮肤纤维症患者刺猬和蜗牛的差异表达

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Objectives: To examine Hedgehog signaling in cutaneous fibrosing disorders for which effective approved therapies are lacking, expand our knowledge of pathophysiology, and explore the rationale for targeted inhibition.

机译：目标：检查缺乏有效经批准的疗法的皮肤纤维症中的刺猬信号，扩大我们对病理生理学的知识，并探索有针对性抑制的理由。

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来源
《American journal of clinical pathology.》 |2016年第6期|共9页
作者
Goyal Amrita; Linskey Katy R.; Kay Jonathan; Duncan Lyn M.; Nazarian Rosalynn M.;
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作者单位

Massachusetts Gen Hosp Pathol Serv Dermatopathol Unit Boston MA 02114 USA;

Massachusetts Gen Hosp Pathol Serv Dermatopathol Unit Boston MA 02114 USA;

UMass Mem Med Ctr Dept Med Div Rheumatol Worcester MA USA;

Massachusetts Gen Hosp Pathol Serv Dermatopathol Unit Boston MA 02114 USA;

Massachusetts Gen Hosp Pathol Serv Dermatopathol Unit Boston MA 02114 USA;

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原文格式 PDF
正文语种 eng
中图分类病理学;
关键词
Dermatopathology; Hedgehog; Snail; Fibrosis; Scleroderma;

机译：皮肤病学;刺猬;蜗牛;纤维化;硬皮病;

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专利

1. Differential Expression of Hedgehog and Snail in Cutaneous Fibrosing Disorders Implications for Targeted Inhibition [J] . Goyal Amrita, Linskey Katy R., Kay Jonathan, American journal of clinical pathology. . 2016,第6期

机译：刺猬和蜗牛在皮肤纤维化疾病中的针对性抑制的差异表达
2. Differential Expression of Hedgehog and Snail in Cutaneous Fibrosing Disorders Implications for Targeted Inhibition [J] . Goyal Amrita, Linskey Katy R., Kay Jonathan, American journal of clinical pathology. . 2016,第6期

机译：针对靶向抑制的皮肤纤维症患者刺猬和蜗牛的差异表达
3. Glyoxalase 1 (GLO1) Inhibition or Genetic Overexpression Does Not Alter Ethanol's Locomotor Effects: Implications for GLO1 as a Therapeutic Target in Alcohol Use Disorders [J] . Barkley-Levenson Amanda M., Lagarda Frances A., Palmer Abraham A. Alcoholism: Clinical and experimental research . 2018,第5期

机译：乙醛酸酶1（GLO1）抑制或遗传过度表达不会改变乙醇的运动效果：对GLO1的影响是酒精使用障碍中的治疗靶标
4. Differential protein expression in macrophages from patients with HIV-associated neurocognitive disorders [C] . Juliana Perez Laspiur, Frances M. Acevedo, Israel Mendez, ASMS Conference on Mass Spectrometry and Allied Topics . 2015

机译：艾滋病毒相关神经认知障碍患者的巨噬细胞中的差异蛋白质表达
5. A Gli-Targeted Cobalt Complex and Nanoparticle Delivery Agents for Hedgehog Pathway Inhibition [D] . Bajema, Elizabeth. 2018

机译：用于刺猬途径抑制的Gli靶向钴络合物和纳米粒子输送剂
6. Glyoxalase (GLO1) inhibition or genetic overexpression does not alter ethanol’s locomotor effects: implications for GLO1 as a therapeutic target in alcohol use disorders [O] . Amanda M Barkley-Levenson, Frances A Lagarda, Abraham A Palmer -1

机译：乙二醛酶（GLO1）的抑制或基因过表达不会改变乙醇的运动效果：对GLO1作为酒精使用障碍的治疗靶标的意义
7. Differential Expression of Hedgehog and Snail in Cutaneous Fibrosing Disorders [O] . Amrita Goyal, Katy R. Linskey, Jonathan Kay, 2016

机译：刺猬和蜗牛的差异表达在皮肤纤维症状

Differential Expression of Hedgehog and Snail in Cutaneous Fibrosing Disorders Implications for Targeted Inhibition

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