Tranexamic acid for the prevention and treatment of postpartum hemorrhage : a review

摘要

Background : Postpartum hemorrhage (PPH) is a frequent complication and a major cause of maternal death. PPH can be due to retained placenta, uterine atony, genital tract trauma or coagulopathy. Tranexamic acid (TA), an anti-fibrinolytic agent, can be useful to prevent or treat PPH. In this review, the effectiveness and safety of TA was evaluated.