Utility of Liquid Biopsy by Improved PNA-LNA PCR Clamp Method for Detecting EGFR Mutation at Initial Diagnosis of Non-Small-Cell Lung Cancer: Observational Study of 190 Consecutive Cases in Clinical Practice

摘要

We reviewed 190 consecutive unselected patients who underwent liquid biopsy for detecting an EGFR mutation. The results indicated that not all patients should be candidates for liquid biopsy at initial diagnosis, while some patients gain benefit from initial liquid biopsy in clinical practice. These real-world data supply useful information in choosing patients appropriate for liquid biopsy.