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3D Printing of Lotus Root‐Like Biomimetic Materials for Cell Delivery and Tissue Regeneration

机译：莲藕的3D打印用于细胞输送和组织再生的莲藕

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Abstract >Biomimetic materials have drawn more and more attention in recent years. Regeneration of large bone defects is still a major clinical challenge. In addition, vascularization plays an important role in the process of large bone regeneration and microchannel structure can induce endothelial cells to form rudimentary vasculature. In recent years, 3D printing scaffolds are major materials for large bone defect repair. However, these traditional 3D scaffolds have low porosity and nonchannel structure, which impede angiogenesis and osteogenesis. In this study, inspired by the microstructure of natural plant lotus root, biomimetic materials with lotus root‐like structures are successfully prepared via a modified 3D printing strategy. Compared with traditional 3D materials, these biomimetic materials can significantly improve in vitro cell attachment and proliferation as well as promote in vivo osteogenesis, indicating potential application for cell delivery and bone regeneration. </abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span><Abstract XMLNS =“http://www.wiley.com/namespaces/wiley”type =“main”xml：lang =“en”> <标题类型=“main”>抽象</ title> 近年来，仿生材料越来越关注。大骨缺损的再生仍然是一个重大的临床挑战。此外，血管化在大骨再生过程中起重要作用，并且微通道结构可以诱导内皮细胞形成基本脉管系统。近年来，3D印刷支架是大型骨缺损修复的主要材料。然而，这些传统的3D支架具有低孔隙率和非通道结构，其阻碍了血管生成和骨质发生。在本研究中，灵感来自天然植物莲藕的微观结构，通过改进的3D印刷策略成功地制备了具有莲藕状结构的仿生材料。与传统的3D材料相比，这些仿生材料可以显着改善体外细胞附着和增殖以及在体内骨质发生中促进，表明细胞输送和骨再生的潜在应用。</ p> </摘要> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-18063/'>《Advanced materials interfaces》</a> <b style="margin: 0 2px;">|</b><span>2017年第12期</span><b style="margin: 0 2px;">|</b><span>共1页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Feng Chun&option=202" target="_blank" rel="nofollow">Feng Chun;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Zhang Wenjie&option=202" target="_blank" rel="nofollow">Zhang Wenjie;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Deng Cuijun&option=202" target="_blank" rel="nofollow">Deng Cuijun;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Li Guanglong&option=202" target="_blank" rel="nofollow">Li Guanglong;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Chang Jiang&option=202" target="_blank" rel="nofollow">Chang Jiang;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Zhang Zhiyuan&option=202" target="_blank" rel="nofollow">Zhang Zhiyuan;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Jiang Xinquan&option=202" target="_blank" rel="nofollow">Jiang Xinquan;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Wu Chengtie&option=202" target="_blank" rel="nofollow">Wu Chengtie;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>State Key Laboratory of High Performance Ceramics and Superfine MicrostructureChinese Academy of Sciences1295 Dingxi Road Shanghai 200050 P. R. China;</p> <p>Department of ProsthodonticsSchool of Medicine639 Zhizaoju Road Shanghai 200011 P. R. China;</p> <p>State Key Laboratory of High Performance Ceramics and Superfine MicrostructureChinese Academy of Sciences1295 Dingxi Road Shanghai 200050 P. R. China;</p> <p>Department of ProsthodonticsSchool of Medicine639 Zhizaoju Road Shanghai 200011 P. R. China;</p> <p>State Key Laboratory of High Performance Ceramics and Superfine MicrostructureChinese Academy of Sciences1295 Dingxi Road Shanghai 200050 P. R. China;</p> <p>Oral and Maxillofacial SurgerySchool of Medicine639 Zhizaoju Road Shanghai 200011 P. R. China;</p> <p>Department of ProsthodonticsSchool of Medicine639 Zhizaoju Road Shanghai 200011 P. R. China;</p> <p>State Key Laboratory of High Performance Ceramics and Superfine MicrostructureChinese Academy of Sciences1295 Dingxi Road Shanghai 200050 P. R. China;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/6960.html" title="特种结构材料">特种结构材料;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=biomimetic materials&option=203" rel="nofollow">biomimetic materials;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=cell delivery&option=203" rel="nofollow">cell delivery;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=lotus root‐like biomaterials&option=203" rel="nofollow">lotus root‐like biomaterials;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=tissue regeneration&option=203" rel="nofollow">tissue regeneration;</a> </p> <div class="translation"> 机译：仿生材料;细胞递送;莲藕状生物材料;组织再生; </div> </li> </ul> </div> </div> <div class="literature cardcommon"> <div class="similarity "> <h3 class="all_title" id="enpatent66">相似文献</h3> <div class="similaritytab clearfix"> <ul> <li class="active" >外文文献</li> <li >中文文献</li> <li >专利</li> </ul> </div> <div class="similarity_details"> <ul > <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/academic-journal-foreign_detail_thesis/0204120813152.html">3D Printing of Lotus Root-Like Biomimetic Materials for Cell Delivery and Tissue Regeneration</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Guanglong Li&option=202" target="_blank" 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