Clinical Characteristics of Adult Tetanus Given Magnesium Sulphate in Intensive Care Unit

摘要

The purpose of this research is to describe the clinical characteristics found in adult tetanus patients given Magnesium sulphate in Intensive Care Unit. The study design is cross-sectional. Subjects of the study are 12 adult tetanus patients admitted to intensive care unit given intravenousmagnesium sulphate drip. The data were collected from medical record. Data analysis was done to get the mean value and presented as descriptive tables. Average age of the adult tetanus patients given magnesium sulphate is 51.3 years old. [Standard Deviation (SD)±17 years], average lengthof stay in hospital is 29.3 days (SD±8.9 days), average duration of mechanical ventilation needed is 9.8 days (SD±9 days), average time needed for swallowing ability to recover is 22.9 days (SD±11.3 days), average time of abdominal spasm occurrence is 10.5 days (SD±7.3days), average time of trismus occurrence is 11.8 days (SD±7 days), average systole pressure is 128.3 mmHg (SD±15.6 mmHg), average diastolic pressure is 72.8 mmHg (SD±10.6 mmHg), average magnesium sulphate drip duration is 16.7 days (SD±7.7 days), average bloodmagnesium concentration is 8.4 mg/dL (SD±3.5 mg/dL), incidence of hypotension is 41.7%, incidence of cardiac arrest is 8.3%. Clinical characteristics of adult tetanus patients given magnesium sulphate to control muscular spasm and autonomic dysfunction are favorable. The length of stayin hospital is almost the same with the average time needed to recover from the tetanus toxin, the duration of mechanical ventilation needed is quite short, the hypotension incidence is acceptable and the cardiac arrest incidence is low. Magnesium sulphate should be considered to be used tocontrol muscle spasm and autonomic dysfunction. In adult patient with tetanus although World Health Organization (WHO) recommend benzodiazepines.