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Association between common bile duct diameter and abdominal aorta calcium score

机译:常见胆管直径与腹主动脉钙分数之间的关联

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Background and objective There is evidence of association between aging and increase in the normal upper limit of the common bile duct (CBD) diameter. As aging is a documented risk factor for atherosclerosis, and the possible effect that atherosclerosis can have on the CBD diameter via affecting its smooth muscle contractility and blood flow, we decided to determine the association between CBD diameter and atherosclerosis in the abdominal aorta (AA). Methods A total of 99 asymptomatic patients (53 males and 46 females; age range of 18–88?years) without history of cholecystectomy who underwent abdominal contrast-enhanced CT scan were included. The CBD diameter was measured. The atherosclerosis of AA was quantified by Agatston score. Results Mean (±?SD) CBD diameter was 6.14 (±?1.95) mm; range?=?2.4–12.7?mm. Agatston score was 0 in 59 patients. In the remaining 40 patients, median (interquartile range, IQR) Agatston score was 497.5 (2026.3). Mean (±?SD) CBD diameter in patients with Agatston score?>?0 was 7.39 (±?2.07) mm compared to 5.29 (±?1.32) mm in patients without calcification plaque ( P ?
机译:背景和目的有证据表明衰老和常规胆管(CBD)直径的正常上限之间的关联。随着衰老的是动脉粥样硬化的记录风险因素,以及动脉粥样硬化可以通过影响其平滑肌肉收缩和血流的CBD直径的可能效果,我们决定确定腹部主动脉(AA)中CBD直径和动脉粥样硬化之间的关联。方法共有99名无症状患者(53名男性和46名女性;年龄范围为18-88岁),没有胆囊切除术的历史涉及接受腹部对比增强的CT扫描。测量CBD直径。 AA的动脉粥样硬化通过agatston得分量化。结果平均值(±3)CBD直径为6.14(±1.95)mm;范围?=?2.4-12.7?mm。 Agatston评分为59名患者。在剩下的40名患者中,中位数(四分位数范围,IQR)Agatston得分为497.5(2026.3)。 agatston评分患者的平均值(±sd)CBD直径?>Δ0为7.39(±2.07)mm,而没有钙化斑块的患者的5.29(±1.32)mm(p?<0.001)。在CBD直径和Agatston得分之间看到了中等的相关性(ρα= 0.43; p?= 0.005)。结论虽然不明白随着推进年龄增长的CBD直径增加的确切原因,但随着衰老发生的一般动脉粥样硬化过程可能会影响CBD的平滑肌。是否应定义正常CBD的上限,或者在评估亚临床或临床动脉粥样硬化需要进一步研究的患者中评估扩张的CBD。

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