Prenatal exposure to PCBs and neurological and sexual/pubertal development from birth to adolescence

摘要

Several chemical compounds are resistant to degradation and end up in the food chain. One group of these chemicals is poly-chlorinated biphenyls (PCBs) which are used as flame retardants and plasticizers. Although PCBs were banned several decades ago, PCBs are still found in environmental media, including in the body of humans. PCBs are transferred from mother to fetus via the placenta during pregnancy. Considering that the prenatal period is a sensitive period during which essential developmental processes take place, exposure to environmental chemicals might have considerable and permanent consequences for outcomes in later life.