Synergistic Interaction Between Heme Oxygenase (HO) and Nuclear-Factor E2-Related Factor-2 (Nrf2) against Oxidative Stress in Cardiovascular Related Diseases

Ndisang Joseph Fomusi

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Synergistic Interaction Between Heme Oxygenase (HO) and Nuclear-Factor E2-Related Factor-2 (Nrf2) against Oxidative Stress in Cardiovascular Related Diseases

机译：血红素氧酶（HO）和核因子E2相关因子-2（NRF2）与心血管相关疾病中氧化应激之间的协同相互作用

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Background: Nuclear factor-erythroid related factor-2 (Nrf2) is a master regulator of transcriptional activation of anti-oxidants in cells. Similarly, heme oxygenase (HO) is a cytoprotective protein with anti-oxidant effects. This review article will shed more light on the interaction between Nrf2 and HO.

机译：背景：核因子 - 红细胞相关因子-2（NRF2）是细胞中抗氧化剂的转录激活的主调节因子。类似地，血红素氧合酶（HO）是一种具有抗氧化效果的细胞保护蛋白。该审查文章将更多地阐明NRF2和HO之间的互动。

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来源
《Current pharmaceutical design 》 |2017年第10期| 共6页
作者
Ndisang Joseph Fomusi;
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作者单位

Univ Saskatchewan Coll Med Dept Physiol 107 Wiggins Rd Saskatoon SK S7N 5E5 Canada;

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原文格式 PDF
正文语种 eng
中图分类药学 ;
关键词
Heme oxygenase; nuclear-factor-E2-related-factor-2; oxidative stress; inflammation; cardiovascular disease;

机译：血红素氧合酶;核因子-e2相关因子-2;氧化应激;炎症;心血管疾病;

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1. Synergistic Interaction Between Heme Oxygenase (HO) and Nuclear-Factor E2-Related Factor-2 (Nrf2) against Oxidative Stress in Cardiovascular Related Diseases [J] . Ndisang Joseph Fomusi Current pharmaceutical design . 2017 ,第10期

机译：血红素氧酶（HO）和核因子E2相关因子-2（NRF2）与心血管相关疾病中氧化应激之间的协同相互作用
2. Identification of heme oxygenase-1 from golden pompano (Trachinotus ovatus) and response of Nrf2/HO-l signaling pathway to copper-induced oxidative stress [J] . Xie Jiajun, He Xuanshu, Fang Haohang, Chemosphere . 2020 ,第Auga期

机译：从金庞帕磷酸（Trachinotus Ovatus）鉴定血红素氧酶-1和NRF2 / HO-L信号通知通向铜诱导氧化应激的响应
3. Synergistic effect of two oxidative stress-related genes (heme oxygenase-1 and GSK3beta) on the risk of Parkinson's disease. [J] . Infante J, Garcia Gorostiaga I, Sanchez Juan P, European journal of neurology: the official journal of the European Federation of Neurological Societies . 2010 ,第5期

机译：两个氧化应激相关基因（血红素加氧酶-1和GSK3beta）对帕金森氏病风险的协同作用。
4. A role for Nrf2 in UVA-mediated heme oxygenase induction and protection from membrane damage in human skin fibroblasts [C] . Haibin Li, Linhao Li, Linhong Deng, Optics in health care and biomedical optics IV . 2010

机译：Nrf2在UVA介导的血红素加氧酶诱导和防止人皮肤成纤维细胞膜损伤中的作用
5. The heme oxygenase/carbon monoxide system in the retina: Biochemistry, anatomy and interactions with the nitric oxide/cGMP pathway. [D] . Cao, Luxiang. 2003

机译：视网膜中的血红素加氧酶/一氧化碳系统：生物化学，解剖结构以及与一氧化氮/ cGMP途径的相互作用。
6. Ganoderma Lucidum Polysaccharides Ameliorates Hepatic Steatosis and Oxidative Stress in db/db Mice via Targeting Nuclear Factor E2 (Erythroid-Derived 2)-Related Factor-2/Heme Oxygenase-1 (HO-1) Pathway [O] . Hong Ning Li, Ling Li Zhao, Di Yi Zhou, 2020

机译：灵芝多糖通过靶向核因子E2（类胡萝卜素衍生的2）-相关因子-2 /血红素加氧酶-1（HO-1）途径缓解db / db小鼠肝脂肪变性和氧化应激
7. Eriodictyol Protects Endothelial Cells against Oxidative Stress-Induced Cell Death through Modulating ERK/Nrf2/ARE-Dependent Heme Oxygenase-1 Expression [O] . Seung Eun Lee, Hana Yang, Gun Woo Son, 2015

机译：圣草酚通过调节ERK / Nrf2 / aRE依赖性血红素加氧酶-1表达保护内皮细胞免受氧化应激诱导的细胞死亡

Synergistic Interaction Between Heme Oxygenase (HO) and Nuclear-Factor E2-Related Factor-2 (Nrf2) against Oxidative Stress in Cardiovascular Related Diseases

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