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Novel Concepts in Psoriatic Arthritis Management: Can W Treat to Target?

机译:银屑病关节炎管理中的新概念:W可以对待目标吗?

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摘要

Purpose of review Psoriatic arthritis (PsA) is a chronic inflammatory spondyloarthritis that can cause progressive joint damage and irreversible disability. Advances in modern therapies, now mean a target of remission is an achievable goal in PsA. There is strong and consistent evidence that a treat-to-target (T21) approach to PsA management results in better patient outcomes; however, the practicalities of incorporating this strategy into routine clinical practice remain a challenge. The heterogeneous nature of this condition and the need for validated outcome measures have to-date hampered consensus on a definition of remission. This review aims to summarise the current T2T research landscape in PsA and highlight potential roles for biomarkers and imaging advances in revolutionising the T2T concept.
机译:审查银屑病关节炎(PSA)的目的是慢性炎症性脊椎炎,可引起逐步的关节损伤和不可逆转的残疾。 现代疗法的进步,现在意味着缓解目标是PSA中可实现的目标。 存在强大而一致的证据表明,对PSA管理的治疗方法(T21)导致更好的患者结果; 然而,将该策略纳入常规临床实践的实用性仍然是一项挑战。 这种条件的异质性质和验证结果措施的需求必须对缓解定义进行禁止的共识。 该审查旨在总结当前T2T研究景观PSA,并突出了革命性化T2T概念的生物标志物和成像的潜在作用。

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