Liposomes as Anticancer Therapeutic Drug Carrier’s Systems: More than a Tour de Force | Bentham Science

摘要

A liposome is a spherical vesicle composed of a bilayer of lipid with centralaqueous cavity. Liposomes are the first nano vesicular drug delivery carriers, which aresuccessfully translated into real-time clinical application and gained great potential in thepast 30 years. The characteristics of liposomes to encapsulate both hydrophilic and hydrophobicdrugs, their biocompatibility and biodegradability make it attractive nanocarriersin drug delivery area. Apart from this, great technical advancement has been made todevelops second-generation liposomes named as stealth liposomes, cationic liposomes,triggered release liposomes and ligand targeted liposomes. This led to widespread use ofliposomes in various areas including anticancer therapeutics, diagnostics and imagingagents. Therefore, the presents review article made an extensive discussion of variousliposomes and its applications in cancer treatment.