A Cationic Nanomicellar Complex of the Quaternary Amphiphilic Amine RC16+with Fenretinide as a New Multitasking System for Antitumor Therapy

Orienti Isabella; Cripe Timothy P.; Currier Mark A.; Cavallari Cristina; Teti Gabriella; Falconi Mirella

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A Cationic Nanomicellar Complex of the Quaternary Amphiphilic Amine RC16+with Fenretinide as a New Multitasking System for Antitumor Therapy

机译：季铵胺RC16 +的阳离子纳米菌络合物，具有短象素作为抗肿瘤治疗的新型多任务系统

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摘要

Objectives: This study investigated the antitumor effect of a new nanomicellar complex obtained by combining the antitumor agent fenretinide with a quaternary amphiphilic amine RC16+ also endowed with antitumor activity.

机译：目的：本研究研究了通过将抗肿瘤剂芬雷雷雷雷雷雷雷雷葡萄酒RC16 +与抗肿瘤活性组合的抗肿瘤剂芬雷雷雷雷葡萄葡萄酒的抗肿瘤效应研究。

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来源
《Current drug delivery 》 |2019年第9期| 共11页
作者
Orienti Isabella; Cripe Timothy P.; Currier Mark A.; Cavallari Cristina; Teti Gabriella; Falconi Mirella;
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作者单位

Univ Bologna Dept Pharm &

Biotechnol Via S Donato 19-2 Bologna Italy;

Nationwide Childrens Hosp Ctr Childhood Canc &

Blood Dis Columbus OH USA;

Nationwide Childrens Hosp Ctr Childhood Canc &

Blood Dis Columbus OH USA;

Univ Bologna Dept Pharm &

Biotechnol Via S Donato 19-2 Bologna Italy;

Univ Bologna Dept Biomed &

Neuromotor Sci DIBINEM Via Irnerio 48 Bologna Italy;

Univ Bologna Dept Biomed &

Neuromotor Sci DIBINEM Via Irnerio 48 Bologna Italy;

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原文格式 PDF
正文语种 eng
中图分类药学 ;
关键词
Cationic nanomicelles; quaternary amphiphilic amine RC16+; fenretinide; ionic interactions; tumor cell; antitumor activity;

机译：阳离子纳米钙;季铵胺胺RC16 +;芬雷雷雷雷雷酸;离子相互作用;肿瘤细胞;抗肿瘤活性;

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1. A Cationic Nanomicellar Complex of the Quaternary Amphiphilic Amine RC16+with Fenretinide as a New Multitasking System for Antitumor Therapy [J] . Orienti Isabella, Cripe Timothy P., Currier Mark A., Current drug delivery . 2019 ,第9期

机译：季铵胺RC16 +的阳离子纳米菌络合物，具有短象素作为抗肿瘤治疗的新型多任务系统
2. Cationic, amphiphilic dextran nanomicellar clusters as an excipient for dry powder inhaler formulation [J] . Vadakkan Mithun Varghese, Raj S. S. Binil, Kartha Chandrasekharan C., Acta biomaterialia . 2015 ,第Null期

机译：阳离子，两亲性葡聚糖纳米胶束簇作为干粉吸入剂配方的赋形剂
3. Cationic, amphiphilic dextran nanomicellar clusters as an excipient for dry powder inhaler formulation [J] . Vadakkan Mithun Varghese, Raj S. S. Binil, Kartha Chandrasekharan C., Acta biomaterialia . 2015 ,第Null期

机译：阳离子，两亲的葡聚糖纳米菌簇作为干粉吸入器配方的赋形剂
4. Silica Beads Grafted with Thermoresponsive Cationic Copolymer Brush Possessing Quaternary Amine Group for Effective Thermoresponsive Ion-exchange Chromatography [C] . Kenichi Nagase, Mike Geven, Saori Kimura, 26th European conference on biomaterials 2014 . 2014

机译：带有热敏阳离子共聚物刷的硅胶珠，具有季胺基团，可实现有效的热敏离子交换色谱
5. Controlling DNA compaction with cationic amphiphiles for efficient delivery systems A step forward towards non-viral Gene Therapy [D] . Savarala, Sushma 2012

机译：用阳离子两亲物控制DNA紧缩以实现有效的递送系统向非病毒基因治疗迈进的一步
6. A Novel Nanomicellar Combination of Fenretinide and Lenalidomide Shows Marked Antitumor Activity in a Neuroblastoma Xenograft Model [O] . Isabella Orienti, Ferro Nguyen, Peng Guan, 2019

机译：Fenretinide和来那度胺的新型Nanomicellar组合在神经母细胞瘤异种移植模型中显示出明显的抗肿瘤活性。
7. >A Novel Nanomicellar Combination of Fenretinide and Lenalidomide Shows Marked Antitumor Activity in a Neuroblastoma Xenograft Model [O] . Isabella Orienti, Ferro Nguyen, Peng Guan, 2019

机译：>新血红素素和萘醛胺的新纳米乳细胞组合在神经母细胞瘤异种移植型号中显示出明显的抗肿瘤活性

A Cationic Nanomicellar Complex of the Quaternary Amphiphilic Amine RC16+with Fenretinide as a New Multitasking System for Antitumor Therapy

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