Clonal or not clonal? Investigating hospital outbreaks of KPC-producing Klebsiella pneumoniae with whole-genome sequencing

Ruppe E.; Olearo F.; Pires D.; Baud D.; Renzi G.; Cherkaoui A.; Goldenberger D.; Huttner A.; Francois P.; Harbarth S.; Schrenzel J.

首页> 外文期刊>Clinical microbiology and infection: European Society of Clinical Microbiology and Infectious Diseases >Clonal or not clonal? Investigating hospital outbreaks of KPC-producing Klebsiella pneumoniae with whole-genome sequencing

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Clonal or not clonal? Investigating hospital outbreaks of KPC-producing Klebsiella pneumoniae with whole-genome sequencing

机译：克隆或不克隆？通过全基因组测序调查医院爆发KPC生产的Klebsiella肺炎

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Objectives: Whole-genome sequencing (WGS) is a promising tool for identifying transmission pathways in outbreaks caused by multidrug-resistant bacteria. However, it is uncertain how the data produced by WGS can be best integrated into epidemiologic investigations.

机译：目的：全基因组测序（WGS）是用于识别由多药抗性细菌引起的爆发中的传输途径的有希望的工具。但是，不确定WGS产生的数据如何最好地集成到流行病学研究中。

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来源
《Clinical microbiology and infection: European Society of Clinical Microbiology and Infectious Diseases 》 |2017年第7期| 共6页
作者
Ruppe E.; Olearo F.; Pires D.; Baud D.; Renzi G.; Cherkaoui A.; Goldenberger D.; Huttner A.; Francois P.; Harbarth S.; Schrenzel J.;
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作者单位

Geneva Univ Hosp Serv Infect Dis Genom Res Lab 4 Rue Gabrielle Perret Gentil CH-1205 Geneva;

Geneva Univ Hosp Infect Control Program Geneva Switzerland;

Geneva Univ Hosp Infect Control Program Geneva Switzerland;

Geneva Univ Hosp Serv Infect Dis Genom Res Lab 4 Rue Gabrielle Perret Gentil CH-1205 Geneva;

Geneva Univ Hosp Dept Genet &

Lab Med Serv Lab Med Bacteriol Lab Geneva Switzerland;

Geneva Univ Hosp Dept Genet &

Lab Med Serv Lab Med Bacteriol Lab Geneva Switzerland;

Univ Hosp Basel Div Clin Microbiol Basel Switzerland;

Geneva Univ Hosp Infect Control Program Geneva Switzerland;

Geneva Univ Hosp Serv Infect Dis Genom Res Lab 4 Rue Gabrielle Perret Gentil CH-1205 Geneva;

Geneva Univ Hosp Infect Control Program Geneva Switzerland;

Geneva Univ Hosp Serv Infect Dis Genom Res Lab 4 Rue Gabrielle Perret Gentil CH-1205 Geneva;

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原文格式 PDF
正文语种 eng
中图分类传染病 ;
关键词
Carbapenemase; Clone; Evolution; Genomics; Klebsiella pneumoniae; Molecular typing; Outbreak; Whole-genome sequencing (WGS);

机译：carbapenemase;克隆;进化;基因组学;Klebsiella肺炎;分子打字;爆发;全基因组测序（WGS）;

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专利

1. Clonal or not clonal? Investigating hospital outbreaks of KPC-producing Klebsiella pneumoniae with whole-genome sequencing [J] . Ruppe E., Olearo F., Pires D., Clinical microbiology and infection: European Society of Clinical Microbiology and Infectious Diseases . 2017 ,第7期

机译：克隆或不克隆？通过全基因组测序调查医院爆发KPC生产的Klebsiella肺炎
2. An Outbreak of Infections Caused by a Klebsiella pneumoniae ST11 Clone Coproducing Klebsiella pneumoniae Carbapenemase-2 and RmtB in a Chinese Teaching Hospital [J] . Jun Li, Ming-Xiang Zou, Hai-Chen Wang, 中华医学杂志（英文版） . 2016 ,第017期

机译：在中国的一家教学医院，由一起生产肺炎克雷伯菌肺炎克雷伯菌Carbapenemase-2和RmtB的肺炎克雷伯菌ST11克隆引起的感染暴发
3. Tracking a hospital outbreak of KPC-producing ST11 Klebsiella pneumoniae with whole genome sequencing [J] . Jiang Y., Wei Z., Wang Y., Clinical microbiology and infection: European Society of Clinical Microbiology and Infectious Diseases . 2015 ,第11期

机译：通过全基因组测序跟踪医院生产KPC的ST11肺炎克雷伯菌的暴发
4. Molecular Cloning and Characterization of Glycerol Dehydrogenase from Klebsiella pneumoniae [C] . Yanhua Liu, Li Zhao, Jianguo Zhang, International conference on applied biotechnology . 2015

机译：肺炎克雷伯菌中甘油脱氢酶的分子克隆与表征
5. Identification, cloning, sequencing, and characterization of a proposed lactacin B enhancer protein and partial characterization of the Lactobacillus delbrueckii ssp. lactis ATCC 4797 genome by shotgun cloning and random sequencing. [D] . Ulrich, Ricky Lee. 1999

机译：鉴定，克隆，测序和拟议的lactacin B增强蛋白的表征以及德氏乳杆菌的部分表征。通过散弹枪克隆和随机测序获得乳酸ATCC 4797基因组。
6. A66 Multi-drug-resistant Klebsiella pneumoniae strains circulating in hospital setting: Whole-genome sequencing and Bayesian phylogenetic analysis for outbreak investigations [O] . E Cella, M Ciccozzi, M Fogolari, 2018

机译：A66在医院环境中传播的耐多药肺炎克雷伯菌菌株：用于暴发调查的全基因组测序和贝叶斯系统发育分析
7. A66 Multi-drug-resistant Klebsiella pneumoniae strains circulating in hospital setting: Whole-genome sequencing and Bayesian phylogenetic analysis for outbreak investigations [O] . E Cella, M Ciccozzi, M Fogolari, 2018

机译：A66多药物抗性肺炎肺炎肺炎在医院环境中循环：爆发调查的全基因组测序和贝叶斯系统发育分析

Clonal or not clonal? Investigating hospital outbreaks of KPC-producing Klebsiella pneumoniae with whole-genome sequencing

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