Efficacy and safety of withholding antimicrobial treatment in children with cancer, fever and neutropenia, with a demonstrated viral respiratory infection: a randomized clinical trial

Santolaya M. E.; Alvarez A. M.; Acuna M.; Aviles C. L.; Salgado C.; Tordecilla J.; Varas M.; Venegas M.; Villarroel M.; Zubieta M.; Toso A.; Bataszew A.; Farfan M. J.; de la Maza V.; Vergara A.; Valenzuela R.; Torres J. P.

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Efficacy and safety of withholding antimicrobial treatment in children with cancer, fever and neutropenia, with a demonstrated viral respiratory infection: a randomized clinical trial

机译：患有癌症，发热和中性粒细胞病毒患儿的抗菌治疗的疗效和安全性，具有显示的病毒呼吸道感染：随机临床试验

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Objectives: To determine efficacy and safety of withholding antimicrobials in children with cancer, fever and neutropenia (FN) with a demonstrated respiratory viral infection.

机译：目的：以表明呼吸道病毒感染确定患有癌症，发热和中性粒细胞病毒（FN）的儿童抗菌药物的疗效和安全性。

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来源
《Clinical microbiology and infection: European Society of Clinical Microbiology and Infectious Diseases》 |2017年第3期|共6页
作者
Santolaya M. E.; Alvarez A. M.; Acuna M.; Aviles C. L.; Salgado C.; Tordecilla J.; Varas M.; Venegas M.; Villarroel M.; Zubieta M.; Toso A.; Bataszew A.; Farfan M. J.; de la Maza V.; Vergara A.; Valenzuela R.; Torres J. P.;
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作者单位

Univ Chile Hosp Dr Luis Calvo Mackenna Fac Med Dept Paediat Santiago Chile;

Univ Chile Hosp San Juan Dios Fac Med Dept Paediat Santiago Chile;

Univ Chile Hosp Dr Roberto Rio Fac Med Dept Paediat Santiago Chile;

Univ Chile Hosp San Borja Arriaran Fac Med Dept Paediat Santiago Chile;

Univ Chile Hosp Dr Exequiel Gonzalez Cortes Dept Paediat Santiago Chile;

Univ Chile Hosp Dr Roberto Rio Fac Med Dept Paediat Santiago Chile;

Natl Child Programme Antineoplast Drugs Network Comm Infect Dis Santiago Chile;

Univ Chile Hosp San Juan Dios Fac Med Dept Paediat Santiago Chile;

Univ Chile Hosp Dr Luis Calvo Mackenna Fac Med Dept Paediat Santiago Chile;

Natl Child Programme Antineoplast Drugs Network Comm Infect Dis Santiago Chile;

Univ Chile Hosp Dr Luis Calvo Mackenna Fac Med Dept Paediat Santiago Chile;

Univ Chile Hosp Dr Luis Calvo Mackenna Fac Med Dept Paediat Santiago Chile;

Univ Chile Hosp Dr Luis Calvo Mackenna Fac Med Dept Paediat Santiago Chile;

Univ Chile Hosp Dr Luis Calvo Mackenna Fac Med Dept Paediat Santiago Chile;

Univ Chile Hosp Dr Luis Calvo Mackenna Fac Med Ctr Mol Studies Santiago Chile;

Univ Chile Hosp Dr Luis Calvo Mackenna Fac Med Dept Paediat Santiago Chile;

Univ Chile Hosp Dr Luis Calvo Mackenna Fac Med Dept Paediat Santiago Chile;

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原文格式 PDF
正文语种 eng
中图分类传染病;
关键词
Antimicrobials; Cancer; Children; Febrile neutropenia; Respiratory viral infection;

机译：抗微生物;癌症;儿童;发热中性粒细胞病;呼吸道病毒感染;

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专利

1. Efficacy and safety of withholding antimicrobial treatment in children with cancer, fever and neutropenia, with a demonstrated viral respiratory infection: a randomized clinical trial [J] . Santolaya M. E., Alvarez A. M., Acuna M., Clinical microbiology and infection: European Society of Clinical Microbiology and Infectious Diseases . 2017,第3期

机译：患有癌症，发热和中性粒细胞病毒患儿的抗菌治疗的疗效和安全性，具有显示的病毒呼吸道感染：随机临床试验
2. Frequency and clinical outcome of respiratory viral infections and mixed viral-bacterial infections in children with cancer, fever and neutropenia [J] . TorresJ.P., Labra?aY., Iba?ezC., The Pediatric infectious disease journal . 2012,第9期

机译：癌症，发烧和中性粒细胞减少症患儿呼吸道病毒感染和病毒-细菌混合感染的频率和临床结局
3. Efficacy and safety of Aviron Rapid in 18-60-year-old patients with clinical diagnosis of acute respiratory viral infection: a multicenter, randomized, double-blind, placebo-controlled clinical trial [J] . Georgi Popov, Margarita Gospodinova-Bliznakova, Zlatko Kalvatchev, Folia medica . 2021,第1期

机译：18-60岁急性呼吸病毒感染患者Aviron Rapid的疗效和安全性：多中心，随机，双盲，安慰剂控制临床试验
4. Efficacy of pulmonary administration of macrolide antimicrobial agents for the treatment of respiratory infections [C] . Annual meeting exposition of the Controlled Release Society . 2009

机译：大环内德抗微生物剂治疗呼吸道感染的疗效疗效
5. Nonparametric and Semiparametric Inference for Treatment Efficacy in Randomized Clinical Trials with a Time-to-event Outcome and Non-compliance. [D] . Zhou, Ying. 2010

机译：非参数和半参数推论具有事件发生时间和不依从性的随机临床试验的疗效。
6. Efficacy and safety of withholding antimicrobial treatment in children with cancer fever and neutropenia with a demonstrated viral respiratory infection: a randomized clinical trial [O] . M.E. Santolaya, A.M. Alvarez, M. Acuña, -1

机译：癌症发烧和中性粒细胞减少症儿童并已证明病毒性呼吸道感染停用抗菌药物的疗效和安全性：一项随机临床试验
7. Faculty Opinions recommendation of Efficacy and safety of withholding antimicrobial treatment in children with cancer, fever and neutropenia, with a demonstrated viral respiratory infection: a randomized clinical trial. [O] . Bob Phillips 2019

机译：教师意见建议扣除癌症，发热和中性粒细胞病患儿童的疗效和安全性的疗效和安全性，具有显示的病毒呼吸道感染：随机临床试验。

Efficacy and safety of withholding antimicrobial treatment in children with cancer, fever and neutropenia, with a demonstrated viral respiratory infection: a randomized clinical trial

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